Jane Grimwood is a British microbiologist.

Early life and education

Grimwood was born in England.[1] Her father was a chemist, and she always wanted to be a scientist as a child.[1] Grimwood was awarded her B.Sc. and Ph.D. in Microbiology from the University of Leeds in the United Kingdom. She did postdoctoral research at the University of Oxford, University of San Francisco and Dartmouth College.

Career

Human Genome Project

Grimwood was an important part of the Human Genome Project effort, working from the Stanford Human Genome Center.[2] Grimwood stated, "I feel very lucky to have been a part of the Human Genome Project. It was arguably the best international collaborative project of our lifetime."[1] She and her team worked on sequencing and analyzing chromosomes 5, 16, and 19 -- "320 million base pairs . . . comprising more than 10% of the human genome."[2] They discovered that chromosome 19 has the highest gene density of any human chromosome, and were able to link certain genes on the chromosome to genetic diseases including insulin-resistant diabetes.[3][4]

Current work

Since the Human Genome Project finished in 2008, Grimwood has led a group of researchers who focus on sequencing and finishing a group of eukaryotic genomes that include fungi, plants, and vertebrates.[2] The lab focuses on the genomes of organisms relevant to the development of sustainable biofuels and global food security. Organisms they have worked on with this goal include "the American poplar, the hardy perennial grass, switchgrass and soybean."[1]

Currently, she is the co-director of the Genome Sequencing Center and Faculty Investigator at the HudsonAlpha Institute for Biotechnology.

In August 2015, the National Science Foundation awarded a $2.4 million grant jointly to a group of five researchers, including Grimwood, to further genomics research involving Upland cotton.[5][6][7]

References

  1. 1 2 3 4 "Get to Know: Jane Grimwood". hudsonalpha.org. Archived from the original on 23 November 2015. Retrieved 2 November 2015.
  2. 1 2 3 "Jane Grimwood". hagsc.org. Archived from the original on 26 November 2015. Retrieved 2 November 2015.
  3. ↑ "GNN - Two More Human Chromosomes Are Complete". www.genomenewsnetwork.org. Retrieved 2017-03-02.
  4. ↑ Grimwood, Jane; Gordon, Laurie A.; Olsen, Anne; Terry, Astrid; Schmutz, Jeremy; Lamerdin, Jane; Hellsten, Uffe; Goodstein, David; Couronne, Olivier (2004-04-01). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–535. Bibcode:2004Natur.428..529G. doi:10.1038/nature02399. ISSN 1476-4687. PMID 15057824.
  5. ↑ JIM MELVIN Clemson University. "COTTON 'MAP': Clemson scientist shares $2.4 million from NSF to advance genomic research". The Times and Democrat. Retrieved 2 November 2015.
  6. ↑ Liz Hurley (27 July 2015). "HudsonAlpha investigator, research partners receive $2M to seque - WAFF-TV: News, Weather and Sports for Huntsville, AL". waff.com. Retrieved 2 November 2015.
  7. ↑ "Clemson scientist shares $2.4 million from NSF to advance cotton genomic research". clemson.edu. Retrieved 2 November 2015.
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