Joseph Berger
Born1951|04|19
Alma materPennsylvania State University, Jefferson Medical College
Known forDiscovered using Oxandrolone for the treatment of AIDS; Research on Progressive Multifocal Leukoencephalopathy (PML), and MS (Multiple Sclerosis)
SpouseSandra T. Berger
Children3

Joseph R. Berger (born April 19, 1951) is an American internist and neurologist who is known[1][2] for his research interests in progressive multifocal leukoencephalopathy (PML), the neurological complications of HIV/AIDS, multiple sclerosis, and other inflammatory disorders of the brain. Particularly, he contributed research on why PML occurs more frequently in AIDS than in other immunosuppressive conditions.[3]

He has also made substantial contributions to the understanding of the spectrum of neurological complications that accompany HIV infection occurring as a consequence of the direct effects of the HIV on the central and peripheral nervous systems and those that result from the accompanying immunosuppression of AIDS. Berger is the discoverer of the value of the anabolic steroid oxandrolone in the treatment of AIDS wasting and AIDS myopathy.[4] He is the recipient of the 2015 Pioneer in NeuroVirology award of the International Society for NeuroVirology.,[5] the 2014 Raymond D. Adams Lectureship, the 2015 Distinguished Teaching Award from the American Neurological Association [6] ; and the 2018 Alumni Achievement Award from the Sidney Kimmel College, Thomas Jefferson University.[7]

Career and education

Berger graduated from Susquehanna Township High School in Harrisburg, PA, in 1969 and was  a summa cum laude graduate of the Pennsylvania State University (1972) – Jefferson Medical College (1974) Five-Year Accelerated Medical Program. He completed his residency in internal medicine at Georgetown University Hospital and his neurology residency at the University of Miami School of Medicine.

In 1981, Berger joined the faculty of the University of Miami School of Medicine, serving in the departments of both neurology and internal medicine. At that institution, he held the Whigham-Berger Endowed Chair for the study of the neurological complications of HIV/AIDS.[8] He is a fellow of the American Academy of Neurology, the American Neurological Association, and the American College of Physicians.

From 1995 through 2014, he was chairman of the Department of Neurology at the University of Kentucky College of Medicine, where he held the Ruth L. Works Professorship and was director of the Multiple Sclerosis Clinic and the Neuro-AIDS Program.

Berger worked in international outreach programs- as he ran a conference for the United Nations and Mother and Children's African Relief Organization in Addis Ababa, Ethiopia in 1999.

In 2014, he joined the faculty of the Perelman School of Medicine, University of Pennsylvania, as professor of neurology and was chief of the Multiple Sclerosis Division from 2014 through 2019.

Berger is the case-report editor of the Journal of NeuroVirology and serves or has served on other editorial boards. He co-founded the International Neuroscience of HIV meeting with Dr. Robert Levy, and has served in numerous administrative capacities for the American Neurological Association and the American Academy of Neurology.

Publications

Berger has published more than 275 refereed papers, more than 100 chapters, and has co-edited four textbooks,  The preponderance of his published work has focused on the progressive multifocal leukoencephalopathy, the neurological complications of HIV/AIDS and other infectious diseases, and multiple sclerosis and related inflammatory conditions; however, his contributions address a large number of other neurological conditions.

  • Berger, Joseph R.; Levy, Robert M., eds. (1997). AIDS and the Nervous System (2nd ed.). Lippincott Williams & Wilkins. ISBN 978-0781703093.
  • Nath, Avindra; Berger, Joseph R., eds. (2003). Clinical Neurovirology. Neurological Disease and Therapy. Informa Healthcare. ISBN 978-0-8247-4081-8.
  • Portegies, Peter; Berger, Joseph, eds. (2007). HIV/AIDS and the Nervous System. Handbook of Clinical Neurology. Vol. 85. Elsevier. ISBN 978-0-444-52010-4.
  • Nath, Avindra; Berger, Joseph R., eds. (2020). Clinical Neurovirology (2nd ed.). CRC Press. ISBN 978-9-004-16042-2.

Media Appearances

Berger has appeared in lectures and on PBS news regarding the effects on the brain of COVID-19, as well other issues such as the need for more neurologists and artificial intelligence usefulness in neurology:

Neurological consequences of COVID-19 on YouTube

The inadequate supply of neurologists on YouTube

Can artificial intelligence replace neurologists on YouTube

References

  1. ↑ Berger, JR; Kaszovitz, B; Post, MJ; Dickinson, G (1987). "Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. A review of the literature with a report of sixteen cases". Annals of Internal Medicine. 107 (1): 78–87. doi:10.7326/0003-4819-107-1-78. PMID 3296901.
  2. ↑ Berger, JR; Houff, S (2006). "Progressive multifocal leukoencephalopathy: Lessons from AIDS and natalizumab". Neurological Research. 28 (3): 299–305. doi:10.1179/016164106X98198. PMID 16687057. S2CID 6341466.
  3. ↑ Berger, Joseph (2003). "Progressive Multifocal Leukoencephalopathy in Acquired Immunodeficiency Syndrome: Explaining the High Incidence and Disproportionate Frequency of the Illness Relative to Other Immunosuppressive Conditions". Journal of Neurovirology. 9 (2): 38–41. doi:10.1080/13550280390195261. PMID 12709870. S2CID 17171153.
  4. ↑ Berger, JR; Pall, L; Hall, CD; Simpson, DM; Berry, PS; Dudley, R (1996). "Oxandrolone in AIDS-wasting myopathy". AIDS. 10 (14): 1657–62. doi:10.1097/00002030-199612000-00010. PMID 8970686. S2CID 9832782.
  5. ↑ ISNV Pioneer
  6. ↑ "Distinguished Neurology Teacher Award | American Neurological Association (ANA)". myana.org. Retrieved 2022-01-07.
  7. ↑ "Sidney Kimmel Medical College Alumni Awards". www.jefferson.edu. Retrieved 2022-01-07.
  8. ↑ "CAMPUS LIFE: Miami; Endowed Chair Recalls Friend Who Had AIDS". The New York Times. 1992-02-09. ISSN 0362-4331. Retrieved 2022-01-07.
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