1875: two-year-old season

As a two-year-old, Kisber showed outstanding ability in home gallops, including trial races in which he gave weight and decisive beatings to high-class stable companions.^[7] He took time to reproduce his home form in public however, and finished unplaced in the July Stakes and third in the Stetchworth Stakes^[8] in the summer of 1875.

In autumn, despite his lack of success, he was aimed at the most important two-year-old races at Newmarket. He was strongly fancied for the Middle Park Plate in October and was heavily backed by his owners. He failed again however, finishing unplaced behind Petrarch. Two weeks later, Kisber finally justified the confidence of his connections with a three-length win over Springfield in the inaugural running of the Dewhurst Stakes,^[9] enabling the Baltazzi brothers to win back the money they had lost on his previous races.^[10]

1876: three-year-old season

Alexander Baltazzi: Kisber ran in his name although the colt was owned jointly with his brother Hector

Kisber made good progress over the winter of 1875–1876 and was regarded as one of the leading contenders for the Derby. He did not run in any of the trial races or the 2000 Guineas however, and there were rumours that he would also miss the Derby. The rumours originated from the difficult financial position of his owners: the Baltazzi brothers were heavily in debt and it seemed possible that Kisber, as their most valuable asset, would be seized by their creditors.^[11] Eventually, the brothers managed to obtain further credit, enabling the colt to run in their colours at Epsom.

On 31 May he started 4/1 second favourite in a field of fifteen. Petrarch, who had won the 2000 Guineas was favourite at 2/1.^[6] Kisber broke quickly, but was then pulled back by Charles Maidment and raced towards the back of the field in the early stages. He turned into the straight in fifth place and moved up to challenge Petrarch for the lead just over a furlong out. Kisber quickly went clear as the favourite weakened and won very easily by five lengths from Forerunner.^[8] The Baltazzi brothers financial position was eased considerably: apart from the prize-money, they took an estimated £100,000 in winning bets.^[12]

A few days after his win at Epsom, Kisber was sent to Longchamp for the Grand Prix de Paris on 11 June, the most important race in France. Kisber started favourite for the 3000m race in front of a large and enthusiastic crowd which included the President of France.^[13] Following an investigation by the French racing officials it was declared that he would not be considered an English horse in the event of his victory. He produced a "wonderful"^[10] performance, leading for most of the way and winning very easily by five lengths from the Oaks winner Enguerrande.^[14] The win took his earnings for the year to £11,173.^[15]

On his final start Kisber was sent to Doncaster for the St Leger, for which he started 7/4 favourite against eight rivals despite rumours that he was having problems in training.^[9] He was certainly not impressive before the race, appearing heavily bandaged on all four legs.^[16] He ran prominently for much of the way but weakened abruptly in the straight and finished a remote fourth behind Petrarch. John Osbourne, who rode him in the race said "He was beaten before he even started".^[11] There was some dissatisfaction with the result from those who felt that Kisber had not shown his true form^[17] and that his owners had never intended him to win.^[18] According to one London correspondent, there were "suspicions of unfairness".^[19]

Kisber was entered in some major races in 1877, and was rumoured to be returning for a match race against Silvio in 1878,^[20] but he never ran again.