LMAN2

LMAN2
Identifiers
Aliases	LMAN2, C5orf8, GP36B, VIP36, lectin, mannose binding 2
External IDs	OMIM: 609551 MGI: 1914140 HomoloGene: 4962 GeneCards: LMAN2
Gene location (Human)
Chr.	Chromosome 5 (human)
End	177,351,840 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,510,596 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; body of pancreas; ; right lobe of liver; ; gallbladder; ; right lobe of thyroid gland; ; monocyte; ; left lobe of thyroid gland; ; canal of the cervix; ; rectum; ; minor salivary gland;
	Top expressed in
	spermatid; ; spermatocyte; ; yolk sac; ; proximal tubule; ; brown adipose tissue; ; lacrimal gland; ; islet of Langerhans; ; lip; ; esophagus; ; ascending aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	mannose binding; heat shock protein binding; metal ion binding; carbohydrate binding; protein binding;
Cellular component	integral component of membrane; cell surface; Golgi apparatus; integral component of plasma membrane; extracellular exosome; endoplasmic reticulum-Golgi intermediate compartment membrane; endoplasmic reticulum; membrane; endoplasmic reticulum-Golgi intermediate compartment; extracellular space; Golgi membrane; endoplasmic reticulum membrane; COPII-coated ER to Golgi transport vesicle;
Biological process	protein transport; positive regulation of phagocytosis; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; transport; endoplasmic reticulum to Golgi vesicle-mediated transport; endoplasmic reticulum organization; Golgi organization;
	Sources:Amigo / QuickGO
Orthologs
	10960
	66890
	ENSG00000169223
	ENSMUSG00000021484
	Q12907
	Q9DBH5
	NM_006816
	NM_025828
	NP_006807
	NP_080104
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicular integral-membrane protein VIP36 is a protein that in humans is encoded by the LMAN2 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000169223 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021484 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nufer O, Mitrovic S, Hauri HP (Apr 2003). "Profile-based data base scanning for animal L-type lectins and characterization of VIPL, a novel VIP36-like endoplasmic reticulum protein". J Biol Chem. 278 (18): 15886–96. doi:10.1074/jbc.M211199200. PMID 12609988.
↑ "Entrez Gene: LMAN2 lectin, mannose-binding 2".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Füllekrug J, Scheiffele P, Simons K (1999). "VIP36 localisation to the early secretory pathway". J. Cell Sci. 112 (17): 2813–21. doi:10.1242/jcs.112.17.2813. PMID 10444376.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519. S2CID 581283.
Søborg C, Madsen HO, Andersen AB, et al. (2003). "Mannose-binding lectin polymorphisms in clinical tuberculosis". J. Infect. Dis. 188 (5): 777–82. doi:10.1086/377183. PMID 12934195.
Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Nawa D, Shimada O, Kawasaki N, et al. (2007). "Stable interaction of the cargo receptor VIP36 with molecular chaperone BiP". Glycobiology. 17 (9): 913–21. doi:10.1093/glycob/cwm067. PMID 17586539.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000169223 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021484 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12609988-5] Nufer O, Mitrovic S, Hauri HP (Apr 2003). "Profile-based data base scanning for animal L-type lectins and characterization of VIPL, a novel VIP36-like endoplasmic reticulum protein". J Biol Chem. 278 (18): 15886–96. doi:10.1074/jbc.M211199200. PMID 12609988.

[entrez-6] "Entrez Gene: LMAN2 lectin, mannose-binding 2".

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References

Further reading