| Latarcin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Latarcin | ||||||||
| Pfam | PF10279 | ||||||||
| InterPro | IPR018802 | ||||||||
| OPM superfamily | 259 | ||||||||
| OPM protein | 2pco | ||||||||
| |||||||||
Latarcins are short antimicrobial peptides from the venom of the spider Lachesana tarabaevi.[1] Latarcins adopt an amphipathic alpha-helical structure in the plasma membrane. Possible pharmacological applications for latarcins include antimicrobial and anticancer treatments.[2]
References
- ↑ Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV (July 2006). "Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity". J. Biol. Chem. 281 (30): 20983–92. doi:10.1074/jbc.M602168200. PMID 16735513.
- ↑ Dubovskii, P.V.; Vassilevski, A.A.; Kozlov, S.A.; Feofanov, A.V.; Grishin, E.V.; Efremov, R.G. (2015). "Latarcins: versatile spider venom peptides". Cellular and Molecular Life Sciences. 72 (23): 4501–4522. doi:10.1007/s00018-015-2016-x. PMID 26286896. S2CID 14177431.
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