List Biological Laboratories
TypePrivate
IndustryBiotechnology
Founded1978 (1978)
Headquarters
Campbell, California
,
United States
Products
  • Bacterial Toxins
  • Research Reagents
ServicesContract Manufacturing
Websitewww.listlabs.com

List Biological Laboratories, also known as List Labs, is a US biotechnology company producing bacterial toxins.[1] Its products are involved in vaccine development, toxin research and infectious disease research worldwide.[2]

History

List Labs was founded in 1978[3] by Linda Shoer, and is headquartered in Campbell, California.[4]

Starting with cholera, the firm developed bacterial proteins for research. When the firm was founded, and for many years after, it was the only manufacturer and supplier for several bacterial exotoxins and lipopolysaccharides (LPS).[5]

In 2015 the firm performed a technology transfer of botulinum toxin manufacturing process to Allergan (for the product now known as Botox).[6] It manufactured the first human grade lipopolysaccaride product for clinical trial use, commissioned by the NIH.[7][8] It was one of the first companies worldwide to manufacture live microbiomes for clinical trial starting in 2012.[9]

References

  1. ↑ "List Labs Introduction". Cedarlane.
  2. ↑ Acquaye-Seedah, E.; Reczek, E. E.; Russell, H. H.; Divenere, A. M.; Sandman, S. O.; Collins, J. H.; Stein, C. A.; Whitehead, T. A.; Maynard, J. A. (2018). "Vaccine Development for the Control of Bordetella Pertussis Infections". Infection and Immunity. 86 (6): e00004-18. doi:10.1128/IAI.00004-18. PMC 5964521. PMID 29581192.
  3. ↑ "List Biological Laboratories". devex.
  4. ↑ "Bloomberg Business". Bloomberg.com.
  5. ↑ "Where to Find a Good Botulinum Neurotxin?". The Scientist.
  6. ↑ "Fluorescence polarization assays for determining clostridal toxin activity".
  7. ↑ Kiers, Dorien; Leijte, G. P.; Gerretsen, J; Zwaag, J; Kox, M; Pickkers, P (2019). "Comparison of different lots of endotoxin and evaluation on in vivo potency over time in the experimental human endotoxemia model". Innate Immunity. 25 (1): 34–45. doi:10.1177/1753425918819754. PMC 6830888. PMID 30782041.
  8. ↑ Van Lier, Dirk; Geven, Christopher; Leijte, Guus P.; Pickkers, Peter (April 2019). "Experimental human endotoxemia as a model of systemic inflammation". Biochimie. 159: 99–106. doi:10.1016/j.biochi.2018.06.014. PMID 29936295. S2CID 49418822.
  9. ↑ "Mapping microbiome manufacturing". BioCentury.
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