| METTL14 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | METTL14, methyltransferase like 14, hmethyltransferase 14, N6-adenosine-methyltransferase subunit | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 616504 MGI: 2442926 HomoloGene: 10865 GeneCards: METTL14 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Methyltransferase like 14 is a protein that in humans is encoded by the METTL14 gene. [5]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000145388 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028114 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Entrez Gene: Methyltransferase like 14". Retrieved 2018-03-20.
Further reading
- Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP (June 2010). "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts". Hum. Mol. Genet. 19 (12): 2497–506. doi:10.1093/hmg/ddq112. PMC 2876884. PMID 20332099.
- Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, Dai Q, Chen W, He C (February 2014). "A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation". Nat. Chem. Biol. 10 (2): 93–5. doi:10.1038/nchembio.1432. PMC 3911877. PMID 24316715.
- Wang X, Feng J, Xue Y, Guan Z, Zhang D, Liu Z, Gong Z, Wang Q, Huang J, Tang C, Zou T, Yin P (June 2016). "Structural basis of N(6)-adenosine methylation by the METTL3-METTL14 complex". Nature. 534 (7608): 575–8. Bibcode:2016Natur.534..575W. doi:10.1038/nature18298. PMID 27281194. S2CID 4448430.
- Śledź P, Jinek M (September 2016). "Structural insights into the molecular mechanism of the m(6)A writer complex". eLife. 5. doi:10.7554/eLife.18434. PMC 5023411. PMID 27627798.
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