MOWSE (for MOlecular Weight SEarch) is a method to identify proteins from the molecular weight of peptides created by proteolytic digestion and measured with mass spectrometry.[1]

Development

The MOWSE algorithm was developed by Darryl Pappin at the Imperial Cancer Research Fund and Alan Bleasby at the SERC Daresbury Laboratory.[2] The probability-based MOWSE score formed the basis of development of Mascot, a proprietary software for protein identification from mass spectrometry data.

See also

References

  1. ↑ Pappin DJ, Hojrup P, Bleasby AJ (June 1993). "Rapid identification of proteins by peptide-mass fingerprinting". Curr. Biol. 3 (6): 327–32. doi:10.1016/0960-9822(93)90195-T. PMID 15335725. S2CID 40203243.
  2. ↑ "A history of Mascot and Mowse". www.matrixscience.com.


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