Mack as a surname may have multiple sources. One source is Gaelic origin, meaning son. Mack is often used as a prefix in many Irish, and Scottish surnames, including MacCarthy and MacDermot. MacDonald, and MacGregor.

Notable people

• Alexander Mack (1679-1739), German/American minister
• Alexander Mack (Medal of Honor) (c. 1834–1907), Civil War Medal of Honor recipient
• Alex Mack (born 1985), American football player
• Alizé Mack (born 1997), American football player
• Allison Mack (born 1982), American actor best known for her role in Smallville
• Andrew Mack (1780–1854), mayor of Detroit in 1834
• Andrew Mack (actor) (1863–1931), American actor and songwriter
• Austin Mack (born 1997), American football player
• Betty Mack (1901–1980), American film actress
• Bill Mack (disambiguation), various people
• Brooklyn Mack, American ballet dancer
• Burton L. Mack (1931 – 2022), American theologian
• Cecil Mack (1883–1944), American composer, lyricist and music publisher
• Chris Mack (disambiguation), various people
• Christy Mack (born 1991), American former pornographic actress
• An American family that started in baseball and has moved into politics:
  • Connie Mack (1862–1956), baseball player, executive, and team owner
  • Earle Mack (1890–1967), Connie's son; baseball player
  • Connie Mack III (born 1940), grandson of Connie and nephew of Earle; politician
  • Connie Mack IV (born 1967), son of Connie III; politician
  • Mary Bono Mack (born 1961), wife of Connie IV; politician and widow of Sonny Bono
• Craig Mack (1970–2018), American rapper
• Darren Mack (born 1961), American criminal and fugitive
• Daryl Mack (1958–2006), American convicted murderer
• David Alan Mack, writer best known for his freelance Star Trek novels
• David Anthony Mack (born 1961), central figure in the LAPD Rampart police corruption scandal
• David S. Mack, American businessman
• Daylon Mack (born 1997), American football player
• Denny Mack (1851–1888), baseball player
• Earle I. Mack (born 1938), businessman and former US Ambassador
• Ebenezer Mack (1791–1849), New York politician
• Edward Mack (1826–1882), also known as E. Mack, was a German-American composer
• Elbert Mack (born 1986), American football cornerback
• Eric Mack (born 1946), American philosopher
• Eric N. Mack, American painter
• Eugen Mack (1907–1978), Swiss gymnast and Olympic Champion
• H. Bert Mack (1912–1992), American real estate developer
• Hans-Joachim Mack (1928–2008), German general
• Helen Mack (1913–1986), American actress
• Ida May Mack, American classic female blues singer and songwriter
• Isaiah Mack (born 1996), American football player
• Jerome D. Mack (a.k.a. Jerry Mack) (1920–1998) was an American banker, real estate investor, political fundraiser and philanthropist in Las Vegas, Nevada.
• Jimmy Mack (broadcaster) (1934–2004), Scottish radio and television presenter
• Joe Mack (disambiguation), various people
• John E. Mack (1929–2004), American psychiatrist, writer, and professor at Harvard Medical School
• John J. Mack (born 1944), CEO of Morgan Stanley
• John M. Mack (1864–1924), also known as Jack Mack, founder of Mack Trucks
• Karen Mack, American television producer for CBS and co-author of three novels from Los Angeles, California.
• Karl Mack von Leiberich (1752–1828), Austrian general, famous for his defeat at Ulm in Napoleon's campaign of 1805
• Katie Mack (astrophysicist), Australian astrophysicist
• Katie Mack (cricketer), Australian cricketer
• Kevin Mack (disambiguation), multiple people
• Khalil Mack (born 1991), American football player
• Kirby Mack (born 1983), American professional wrestler, went by the ring name Krazy K but is best known for the tag team, Team MackTion, that he formed with his brother T.J.
• Kyle Mack (born 1997), American freestyle snowboarder
• Ledarius Mack (born 1996), American football player
• Lee Mack (born 1968), stage name for English stand-up comedian Lee Gordon McKillop.
• Lonnie Mack (1941–2016), stage name of American blues-rock guitarist and singer, Lonnie McIntosh
• Max Mack (1884–1973), German silent screenwriter and film director
• Marlon Mack (born 1996), American football player
• Mary Mack, American stand-up comedian
• Mirren Mack, Scottish actress
• Myrna Mack (1949–1990), Guatemalan anthropologist, murdered because of her criticism towards the government's abuses during Guatemalan Civil War.
• Nate Mack (1891–1965), Polish-born American banker; co-founder of the Bank of Las Vegas.
• Norman Edward Mack (1855–1932), editor and publisher of the Buffalo Daily Times
• Oliver Mack (born 1957), retired American professional basketball player
• Parker Mack (born 1996), American actor
• Peter F. Mack, Jr. (1916–1986), former U.S. politician
• Ray Mack (1916–1969), American professional baseball player
• Raymond Mack (1927–2011), American sociologist
• Red Mack (1937–2021), American football wide receiver and halfback
• Reinhold Mack, record producer known for working with Electric Light Orchestra, Queen and other rock bands
• Rico Mack (born 1971), American football player
• Robert Mack (1959–2020), Austrian ice hockey player
• Rodney Mack, ring name of professional wrestler Rodney Begnaud
• Sir Ronald Mack, Australian politician
• Ronnie Mack (1940–1963), American songwriter
• Russell Mack (1892 – 1972) American vaudeville performer, stage actor, film director, and producer
• Sam Mack (born 1970), retired American professional basketball player
• Shane Mack (baseball) (born 1963), former left and center fielder
• Sherman Q. Mack (born 1972), Louisiana politician
• Shorty Mack (born 1981), international rapper and actor
• Steve Mack (born 1979), Tara Mack (born 1983), Minnesota politician and a member of the Minnesota House of Representatives
• Ted Mack (radio-TV host) (1904–1976), host of Ted Mack and the Original Amateur Hour on radio and television
• Timothy Mack (born 1972), American pole vaulter and Olympic champion
• Tom Mack (born 1943), former left guard
• Warner Mack (1935-2022), American musician
• Wayne Mack, sportscaster
• Willard Mack (1873–1934), Canadian-born actor, director, and playwright
• William Mack (disambiguation), various people

Fictional characters

• Andi, Rebecca “Bex”, and Celia Mack from Disney Channel series Andi Mack; later Bowie when he marries Bex
• The title character for the 1990s show The Secret World of Alex Mack
• Mark Mack, character in the HBO series Oz