NOSIP

NOSIP
Identifiers
Aliases	NOSIP, CGI-25, nitric oxide synthase interacting protein
External IDs	OMIM: 616759 MGI: 1913644 HomoloGene: 9315 GeneCards: NOSIP
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,590,262 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,727,634 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; triceps brachii muscle; ; blood; ; gastrocnemius muscle; ; sperm; ; vastus lateralis muscle; ; lymph node; ; spleen; ; canal of the cervix; ; amniotic fluid;
	Top expressed in
	spermatid; ; spermatocyte; ; interventricular septum; ; lip; ; blastocyst; ; internal carotid artery; ; morula; ; yolk sac; ; external carotid artery; ; seminiferous tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; transferase activity; RNA binding; ubiquitin protein ligase activity;
Cellular component	cytoplasm; cytosol; Golgi membrane; nucleus;
Biological process	negative regulation of catalytic activity; negative regulation of nitric-oxide synthase activity; multicellular organism development; protein ubiquitination; regulation of nitric-oxide synthase activity;
	Sources:Amigo / QuickGO
Orthologs
	51070
	66394
	ENSG00000142546
	ENSMUSG00000003421
	Q9Y314
	Q9D6T0
	NM_001270960; NM_015953; NM_001363649
	NM_001163684; NM_025533
	NP_001257889; NP_057037; NP_001350578
	NP_001157156; NP_079809
	Wikidata
View/Edit Human	View/Edit Mouse

Nitric oxide synthase-interacting protein is an enzyme that in humans is encoded by the NOSIP gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000142546 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000003421 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Dedio J, Konig P, Wohlfart P, Schroeder C, Kummer W, Muller-Esterl W (Jan 2001). "NOSIP, a novel modulator of endothelial nitric oxide synthase activity". FASEB J. 15 (1): 79–89. doi:10.1096/fj.00-0078com. PMID 11149895. S2CID 34485514.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
↑ "Entrez Gene: NOSIP nitric oxide synthase interacting protein".

Schleicher M, Brundin F, Gross S, et al. (2005). "Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton". Mol. Cell. Biol. 25 (18): 8251–8. doi:10.1128/MCB.25.18.8251-8258.2005. PMC 1234313. PMID 16135813.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Dreyer J, Schleicher M, Tappe A, et al. (2005). "Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity". J. Neurosci. 24 (46): 10454–65. doi:10.1523/JNEUROSCI.2265-04.2004. PMC 6730309. PMID 15548660.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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