NT5C1A
Identifiers
Aliases	NT5C1A, CN-I, CN-IA, CN1, CN1A, CNI, 5'-nucleotidase, cytosolic IA
External IDs	OMIM: 610525 MGI: 2155700 HomoloGene: 57173 GeneCards: NT5C1A
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p34.2 Start 39,651,229 bp[1] End 39,672,107 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D2.2 Start 123,095,297 bp[2] End 123,110,068 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle striated muscle tissue skeletal muscle tissue right atrium left ventricle cerebellar cortex cerebellar hemisphere prefrontal cortex body of pancreas Brodmann area 9 Top expressed in skeletal muscle tissue quadriceps femoris muscle adrenal gland cerebellum cerebellar cortex hippocampus proper circulatory system heart hypothalamus superior frontal gyrus More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding hydrolase activity magnesium ion binding protein binding 5'-nucleotidase activity Cellular component cytoplasm cytosol Biological process nucleoside metabolic process adenosine metabolic process purine nucleotide catabolic process nucleotide metabolic process pyrimidine nucleoside catabolic process dephosphorylation purine nucleoside monophosphate catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84618 230718 Ensembl ENSG00000116981 ENSMUSG00000054958 UniProt Q9BXI3 A3KFX0 RefSeq (mRNA) NM_032526 NM_001085502 RefSeq (protein) NP_115915 NP_001078971 Location (UCSC) Chr 1: 39.65 – 39.67 Mb Chr 4: 123.1 – 123.11 Mb PubMed search [3] [4]
Wikidata
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5'-nucleotidase, cytosolic IA is a protein that in humans is encoded by the NT5C1A gene.^[5]

Function

Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates.^[5]

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.