Portsmouth to Milton (Spaulding Turnpike)

For the section of NH 16 between Portsmouth and Milton, see the Spaulding Turnpike article.

Milton to Bartlett

From Milton, NH 16 continues north, roughly paralleling the Maine border. In Wakefield, the road takes a turn to the northwest heading towards Ossipee. NH 16 turns back to a northerly heading near Tamworth, then makes a turn eastward in Albany to reach Conway. NH 16 turns north again in Conway, entering the region known as the Mount Washington Valley, and begins a concurrency with US 302 at the south end of the village of North Conway. North of North Conway, in Bartlett, the southern NH 16A loop departs and rejoins NH 16 / US 302 before the road makes a westward hook.

Glen to Wentworth Location

In Glen, NH 16 turns north from US 302 and heads toward Jackson, where the northern NH 16A loop is located, as well as NH 16B, which is a loop that begins and ends at NH 16A. Continuing north, NH 16 passes through Pinkham Notch, to the east of Mount Washington, New Hampshire's highest peak, and intersecting with the base of the Mount Washington Auto Road. Route 16 meets US 2 in Gorham, sharing a short concurrency along Gorham's Main Street. Leaving US 2, Route 16 continues north along the Androscoggin River to the city of Berlin, then follows the river north through the towns of Milan and Dummer, and the township of Cambridge, into the town of Errol. From Errol NH 16 continues northeast to Wentworth Location and the Maine border. After crossing the border the road becomes Maine State Route 16 and heads east toward Rangeley.

New Hampshire Route 16A

New Hampshire Route 16A is a designation held by two separate state highways in New Hampshire. Although not directly connected, the two routes are linked by their parent route, New Hampshire Route 16.

Southern segment

New Hampshire Route 16A
Location	Bartlett
Length	2.484 mi[1] (3.998 km)

The southern segment of NH 16A is a loop road, known locally as the Intervale Resort Loop, entirely in the town of Bartlett. It splits off from U.S. Route 302 and NH 16, runs parallel to the highway for 2.484 miles (3.998 km), then rejoins US 302 and NH 16.

Officially, this section of NH 16A is also designated U.S. Route 302 Business, but is not signed as such anywhere along the route.^[6] This is a rare instance of a hidden route in New Hampshire and is interesting in that a duplicate state numbering has been given precedence over a unique federal one.

New Hampshire Route 16B

New Hampshire Route 16B is a 5.381-mile-long (8.660 km) long state highway located entirely in Jackson. Although the road is signed north–south, NH 16B is a nearly-complete loop, beginning and ending at intersections with NH 16A roughly 500 feet (150 m) apart. Heading counterclockwise on NH 16B (signed "north") from NH 16A, NH 16B is known as Black Mountain Road, Moody Farm Road, and Carter Notch Road. The entire route has also been known as Five Mile Circuit Road, in reference to its length.^[8]

In addition to its present designation, NH 16B has been assigned to several old alignments of NH 16, but those other routes are no longer officially designated as such.

In Ossipee, NH 16B was once the designation for an old alignment of NH 16 through the village of Center Ossipee that has been bypassed by the present NH 16 southwest of Ossipee Lake. The route, 2.52 miles (4.06 km) in length, is still called "Route 16B" on street blade signs.^[9][10]

Two other roads have also held the NH 16B designation. One is a local road called Old Rochester Road in Somersworth and Old Dover Road in Rochester, paralleling the Spaulding Turnpike in those two towns from NH 108 to NH 125. There is no longer any signage along the road indicating that the road was designated NH 16B.^[9][11]

The other road followed what is now NH 125 between NH 16 near Union and NH 153 in Union, as well as NH 153 from NH 125 north to NH 16 in Wakefield. The section of NH 125 in Carroll County is still shown as NH 16B on several maps.^[9][12]