Opentrons are liquid handling robots driven by open source software, which can be used by scientists to manipulate small volumes of liquids for the purpose of undertaking biochemical or chemical reactions. The instrument is used primarily by researchers and scientists interested in DIY biology but is increasingly being used by other biologists.[1] They are produced by Opentrons Labworks.

Products

  • OT-1: The OpenTrons OT-1 was the result of a crowd funding campaign on the Kickstarter platform and was released in 2015 for $2,000.[2][3] This robot employed adapters to actuate handheld micropipettes. The release of the OT-1 marked the first commercial open source liquid handling robot in the life science industry. It was also the last in the series to adhere to open hardware standards,[4][5] however, editable CAD files were not released. It is no longer commercially available,[6] though at least one replication was attempted.[7]
  • OT-2: The OpenTrons OT-2 was released in 2018 and has seen utilization as one of the tools that researchers are leveraging in the fight against COVID-19.[8][9][10] The OT-2 and later products, including its electronic micropipettes and hardware modules, are closed source (propietary) hardware. Only coarse CAD files for the enclosure have been released,[11] with no details on the internals, such that it no longer complies with current open hardware standards.[4][5] The software remains open source.

References

  1. ↑ May, Mike (2019-05-20). "A DIY approach to automating your lab". Nature. 569 (7757): 587–588. Bibcode:2019Natur.569..587M. doi:10.1038/d41586-019-01590-z. PMID 31110319.
  2. ↑ "This Robot Could Make Creating New Life Forms As Easy As Coding An App". Wired. 2014-11-20. Retrieved 2020-10-10.
  3. ↑ "DIYBio Comes of Age". Wired. 2014-11-07. Retrieved 2020-10-10.
  4. 1 2 "Open Source Hardware Definition (OSHWA)". www.oshwa.org. 2012-05-26. Retrieved 2023-12-02.
  5. 1 2 "DIN SPEC 3105 OSH - Open Source Hardware - Open Source". din.one. Retrieved 2023-12-02.
  6. ↑ "Sunsetting the OT-One".
  7. ↑ Jockey, Pipette (2018-01-03). "Making a Opentrons compatible liquid handling robot". Pipette Jockey. Retrieved 2023-12-02.
  8. ↑ Walker, Kenneth T.; Donora, Matthew; Thomas, Anthony; Phillips, Alexander James; Ramgoolam, Krishma; Pilch, Kjara S; Oberacker, Phil; Jurkowski, Tomasz Piotr; Gosman, Rares Marius; Fleiss, Aubin; Perkins, Alex; MacKenzie, Neil; Zuckerman, Mark; Danovi, Davide; Steiner, Helene; Meany, Thomas (2020). "CONTAIN:An open-source shipping container laboratory optimised for automated COVID-19 diagnostics" (PDF). Pre-print. doi:10.1101/2020.05.20.106625. S2CID 218859877.
  9. ↑ Villanueva-Cañas, José Luis; Gonzalez-Roca, Eva; Unanue, Aitor Gastaminza; Titos, Esther; Martínez Yoldi, Miguel Julián; Vergara Gómez, Andrea; Puig Butillé, Joan Antón (2020). "ROBOCOV: An affordable open-source robotic platform for SARS-CoV-2 testing by RT-qPCR" (PDF). Pre-print. doi:10.1101/2020.06.11.140285. S2CID 219689351.
  10. ↑ Maia Chagas, Andre; Molloy, Jennifer C.; Prieto-Godino, Lucia L.; Baden, Tom (2020). "Leveraging open hardware to alleviate the burden of COVID-19 on global health systems". PLOS Biology. 18 (4): e3000730. doi:10.1371/journal.pbio.3000730. ISSN 1545-7885. PMC 7182255. PMID 32330124.
  11. ↑ "Opentrons OT-2 Reference Model". GitHub. Retrieved 2023-12-02.
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