PTENP1
Identifiers
AliasesPTENP1, PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN, phosphatase and tensin homolog pseudogene 1
External IDsOMIM: 613531 GeneCards: PTENP1
Orthologs
SpeciesHumanMouse
Entrez

11191

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Ensembl

ENSG00000237984

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)Chr 9: 33.67 – 33.68 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1, also known as PTENP1, is a human pseudogene.[3] which has a partial reactivated function as a competing endogenous RNA regulating the tumor suppressor gene PTEN.[4]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000237984 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: PTENP1 phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1".
  4. Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP (June 2010). "A coding-independent function of gene and pseudogene mRNAs regulates tumour biology". Nature. 465 (7301): 1033–8. Bibcode:2010Natur.465.1033P. doi:10.1038/nature09144. PMC 3206313. PMID 20577206.*Lay summary in: Buehler J (September 1, 2021). "The Complex Truth About 'Junk DNA'". Quanta Magazine.

Further reading


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