Purine analogues are antimetabolites that mimic the structure of metabolic purines.

Examples

Medical uses

Purine antimetabolites are commonly used to treat cancer by interfering with DNA replication.[1]

References

  1. Parker, William B. (2009). "Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer". Chem Rev. 109 (7): 2880–2893. doi:10.1021/cr900028p. PMC 2827868. PMID 19476376.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.