RCBTB2
Identifiers
AliasesRCBTB2, CHC1L, RLG, RCC1 and BTB domain containing protein 2
External IDsOMIM: 603524 MGI: 1917200 HomoloGene: 970 GeneCards: RCBTB2
Orthologs
SpeciesHumanMouse
Entrez

1102

105670

Ensembl

ENSG00000136161

ENSMUSG00000022106

UniProt

O95199

Q99LJ7

RefSeq (mRNA)

NM_001170694
NM_134083

RefSeq (protein)

NP_001164165
NP_598844

Location (UCSC)Chr 13: 48.49 – 48.53 MbChr 14: 73.36 – 73.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RCC1 and BTB domain-containing protein 2 is a protein that in humans is encoded by the RCBTB2 gene.[5][6]

This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000136161 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022106 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Devilder MC, Cadoret E, Cherel M, Moreau I, Rondeau G, Bezieau S, Moisan JP (Jan 1999). "cDNA cloning, gene characterization and 13q14.3 chromosomal assignment of CHC1-L, a chromosome condensation regulator-like guanine nucleotide exchange factor". Genomics. 54 (1): 99–106. doi:10.1006/geno.1998.5498. PMID 9806834.
  6. 1 2 "Entrez Gene: RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2".

Further reading


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