Regina G. Ziegler | |
|---|---|
 Ziegler in 2009 | |
| Alma mater | Swarthmore College University of California, Berkeley Harvard T.H. Chan School of Public Health |
| Scientific career | |
| Fields | Biochemistry, cancer and nutritional epidemiology |
| Institutions | National Cancer Institute |
Regina Gale Ziegler is an American biochemist and nutritional epidemiologist who researched dietary, nutritional, anthropometric, and hormonal determinants of cancer risk. She was a senior investigator in the National Cancer Institute's epidemiology and biostatistics program.
Life
Ziegler received a B.A. from Swarthmore College.[1] She completed a Ph.D. in biochemistry from the University of California, Berkeley.[1] Her 1971 dissertation was titled, Affinity labelling lysozyme with a carbene.[2] She earned a M.P.H. from Harvard T.H. Chan School of Public Health.[1] After graduate school, she taught international nutrition and global food resources courses at Yale University, Harvard University, and Tufts University.[1]
Ziegler joined the National Cancer Institute (NCI) in 1979, was tenured in 1987, and has served most recently as a senior investigator in the epidemiology and biostatistics program.[1] Ziegler’s research has focused broadly on dietary, nutritional, anthropometric, and hormonal determinants of cancer risk.[1] Her early work helped characterize the role of vegetables and fruits, individual carotenoids, folate and one-carbon metabolism in cancer etiology.[1] In addition, she has conducted a number of breast cancer studies with emphasis on anthropometry, diet and endogenous hormones and growth factors.[1] She helped design and direct a large, population-based case-control study of breast cancer in Asian-American women to elucidate the modifiable exposures, related to lifestyle and/or environment, that explained the 6-fold difference in breast cancer incidence between Asia and the West.[1] Ziegler collaboratively developed an international pooled analysis of circulating vitamin D concentrations in relation to risk of colorectal and breast cancer.[1]
Ziegler applied her training in chemistry and biochemistry to the development of new and improved methods for measuring various hormones and nutrients in epidemiologic studies.[1] She played a critical role in the successful development of a sensitive assay for assessment of estrogen metabolites and a validated assay for concurrent measurement of the major steroid hormones.[1] Ziegler is a fellow of the American Society for Nutrition and helped establish its nutritional epidemiology research interest section.[1]
Ziegler retired in October 2018.[1]
References
- 1 2 3 4 5 6 7 8 9 10 11 12 13 14 "Ziegler Retires from NCI". NIH Record. 2018-11-30. Retrieved 2022-10-25.
This article incorporates text from this source, which is in the public domain. - ↑ Ziegler, Regina Gale (1971). Affinity labelling lysozyme with a carbene (Ph.D. thesis). University of California, Berkeley. OCLC 17901294.
This article incorporates public domain material from websites or documents of the National Institutes of Health.