Major surface glycoprotein G
Identifiers
SymbolGlycoprotein_G
PfamPF00802
InterProIPR000925
SCOP21brv / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Major surface glycoprotein G
Identifiers
OrganismHuman respiratory syncytial virus A (strain A2)
SymbolG
PDB5WN9
UniProtP03423
Search for
StructuresSwiss-model
DomainsInterPro

Respiratory syncytial virus G protein is a glycoprotein produced by respiratory syncytial virus.[1][2][3] Some features of the G protein suggest it could be important to respiratory syncytial virus vaccine or antiviral drug target design. [4][5]

References

  1. ↑ Harcourt J, Alvarez R, Jones LP, Henderson C, Anderson LJ, Tripp RA (February 2006). "Respiratory syncytial virus G protein and G protein CX3C motif adversely affect CX3CR1+ T cell responses". Journal of Immunology. 176 (3): 1600–8. doi:10.4049/jimmunol.176.3.1600. PMID 16424189.
  2. ↑ Li XQ, Fu ZF, Alvarez R, Henderson C, Tripp RA (January 2006). "Respiratory syncytial virus (RSV) infects neuronal cells and processes that innervate the lung by a process involving RSV G protein". Journal of Virology. 80 (1): 537–40. doi:10.1128/JVI.80.1.537-540.2006. PMC 1317531. PMID 16352577.
  3. ↑ Zlateva KT, Lemey P, Moës E, Vandamme AM, Van Ranst M (July 2005). "Genetic variability and molecular evolution of the human respiratory syncytial virus subgroup B attachment G protein". Journal of Virology. 79 (14): 9157–67. doi:10.1128/JVI.79.14.9157-9167.2005. PMC 1168771. PMID 15994810.
  4. ↑ Li X, Sambhara S, Li CX, Ettorre L, Switzer I, Cates G, James O, Parrington M, Oomen R, Du RP, Klein M (March 2000). "Plasmid DNA encoding the respiratory syncytial virus G protein is a promising vaccine candidate". Virology. 269 (1): 54–65. doi:10.1006/viro.2000.0186. PMID 10725198.
  5. ↑ Anderson LJ, Jadhao SJ, Paden CR, Tong S (July 2021). "Functional Features of the Respiratory Syncytial Virus G Protein". Viruses. 13 (7): 1214. doi:10.3390/v13071214. PMC 8310105. PMID 34372490.

Further reading

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