Reticuloendotheliosis virus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Ortervirales
Family: Retroviridae
Genus: Gammaretrovirus
Species:
Reticuloendotheliosis virus

Reticuloendotheliosis (RE) designates a group of pathologic syndromes caused by the reticuloendotheliosis virus (REV) group of avian retroviruses. The disease syndromes associated with REV include 1) a runting disease syndrome, 2) chronic neoplasia of lymphoid and other tissues, and 3) acute reticulum cell neoplasia.[1]

Scientific Significance

Reticuloendotheliosis virus represents a third distinct etiological group of avian viral neoplasms, after Marek's disease and avian leukosis virus. The various syndromes caused by REV resemble both Marek's and avian leukosis. It is especially seen in chickens, quail, geese, ducks, and turkeys.[2]

The virus presents some unusual characteristics, such as a similarity to mammalian retroviruses and its presence in the genome of some large DNA viruses. To explain them a theory based on iatrogenic origin was proposed.[3]

Resources

The Avian Diagnostic and Oncology Laboratory, in East Lansing, MI is the primary laboratory for research in REV and other tumor viruses.[4]

The American Association of Avian Pathologists maintains a fact sheet on viral tumor diseases.[5]

References

  1. ↑ Swayne, David E.; Glisson, John R. (2013). Diseases of poultry (13th ed.). Ames, Iowa: John Wiley & Sons. ISBN 978-0470958995.
  2. ↑ John Dunn, DVM, MS, PhD (October 2019). "Reticuloendotheliosis in Poultry". Merck Veterinary Manual.{{cite web}}: CS1 maint: multiple names: authors list (link)
  3. ↑ Niewiadomska, Anna Maria; Gifford, Robert J. (27 August 2013). "The Extraordinary Evolutionary History of the Reticuloendotheliosis Viruses". PLOS Biology. 11 (8): e1001642. doi:10.1371/journal.pbio.1001642. PMC 3754887. PMID 24013706.
  4. ↑ "Avian Diagnostic and Oncology Laboratory".
  5. ↑ "Frequently Asked Questions on Viral Tumor Diseases - Compiled by the AAAP Tumor Virus Committee".
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