SH2D2A
Identifiers
AliasesSH2D2A, F2771, SCAP, TSAD, VRAP, SH2 domain containing 2A
External IDsOMIM: 604514 MGI: 1351596 HomoloGene: 2958 GeneCards: SH2D2A
Orthologs
SpeciesHumanMouse
Entrez

9047

27371

Ensembl

ENSG00000027869

ENSMUSG00000028071

UniProt

Q9NP31

Q9QXK9

RefSeq (mRNA)

NM_001161441
NM_001161442
NM_001161443
NM_001161444
NM_003975

NM_001025571
NM_021309

RefSeq (protein)

NP_001154913
NP_001154914
NP_001154915
NP_001154916
NP_003966

NP_001020742
NP_067284

Location (UCSC)Chr 1: 156.81 – 156.82 MbChr 3: 87.75 – 87.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SH2 domain-containing protein 2A is a protein that in humans is encoded by the SH2D2A gene.[5][6]

Interactions

SH2D2A has been shown to interact with MAP3K2.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000027869 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028071 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Spurkland A, Brinchmann JE, Markussen G, Pedeutour F, Munthe E, Lea T, Vartdal F, Aasheim HC (February 1998). "Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites". The Journal of Biological Chemistry. 273 (8): 4539–46. doi:10.1074/jbc.273.8.4539. PMID 9468509.
  6. "Entrez Gene: SH2D2A SH2 domain protein 2A".
  7. Sun W, Kesavan K, Schaefer BC, Garrington TP, Ware M, Johnson NL, Gelfand EW, Johnson GL (February 2001). "MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway". The Journal of Biological Chemistry. 276 (7): 5093–100. doi:10.1074/jbc.M003719200. PMID 11073940.

Further reading


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