SHB
Identifiers
AliasesSHB, bA3J10.2, SH2 domain containing adaptor protein B
External IDsOMIM: 600314 MGI: 98294 HomoloGene: 74458 GeneCards: SHB
Orthologs
SpeciesHumanMouse
Entrez

6461

230126

Ensembl

ENSG00000107338

ENSMUSG00000044813

UniProt

Q15464

Q6PD21

RefSeq (mRNA)

NM_003028

NM_001033306

RefSeq (protein)

NP_003019

NP_001028478

Location (UCSC)Chr 9: 37.92 – 38.07 MbChr 4: 45.42 – 45.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SH2 domain-containing adapter protein B is a protein that in humans is encoded by the SHB gene.[5][6]

Interactions

SHB (gene) has been shown to interact with:

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000107338 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000044813 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Yulug IG, Hillermann R, Fisher EM (Dec 1994). "The SHB adaptor protein maps to human chromosome 9". Genomics. 24 (3): 615–7. doi:10.1006/geno.1994.1681. PMID 7713524.
  6. "Entrez Gene: SHB Src homology 2 domain containing adaptor protein B".
  7. 1 2 3 4 Karlsson T, Songyang Z, Landgren E, Lavergne C, Di Fiore PP, Anafi M, Pawson T, Cantley LC, Claesson-Welsh L, Welsh M (Apr 1995). "Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins". Oncogene. 10 (8): 1475–83. PMID 7537362.
  8. Lindholm CK, Gylfe E, Zhang W, Samelson LE, Welsh M (Sep 1999). "Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells". The Journal of Biological Chemistry. 274 (39): 28050–7. doi:10.1074/jbc.274.39.28050. PMID 10488157.
  9. 1 2 3 4 Lindholm CK, Henriksson ML, Hallberg B, Welsh M (Jul 2002). "Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells". European Journal of Biochemistry. 269 (13): 3279–88. doi:10.1046/j.1432-1033.2002.03008.x. PMID 12084069.

Further reading


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