Sanjay Asthana
Alma materUniversity College of Medical Sciences University of Delhi, New Delhi, India
Known forAlzheimer's disease research
Scientific career
InstitutionsUniversity of Wisconsin-Madison

Sanjay Asthana is Chief of the Division of Geriatrics and Gerontology at the University of Wisconsin School of Medicine and Public Health, and holds the Duncan G. and Lottie H. Ballantine Endowed Chair in Geriatrics.[1] Since 2009, Asthana has also served as Director of the Wisconsin Alzheimer's Disease Research Center.[2]

In 2015, Asthana was appointed the first Associate Dean for Gerontology.[3] He also holds an appointment at William S. Middleton Memorial Veterans Hospital, where he serves as the Director of the Geriatric Research, Education and Clinical Center.[4]

Asthana's father, an economist and diplomat for the United Nations, suffered from Alzheimer's disease, spurring Ashtana to study the disease.[5]

Asthana has participated in clinical trials of therapeutic interventions, including those testing the effects of soy isoflavones,[6] vitamin E,[7] and ramipril,[8] finding that vitamin E may slow cognitive decline. Other recent work has focused on the possibility that insulin resistance may increase the risk of developing Alzheimer's disease or the progression of the disease.[9][10]

References

  1. ↑ "UWSMPH Directory and Biography".
  2. ↑ "New Alzheimer's Research Center Opens".
  3. ↑ "New Role, Tremendous Vision: Sanjay Asthana, MD, Associate Dean for Gerontology".
  4. ↑ "UWSMPH Director and Bio".
  5. ↑ "Personal Experiences Inspire Alzheimer's Research".
  6. ↑ Gleason, Carey E.; Fischer, Barbara L.; Dowling, N. Maritza; Setchell, Kenneth D. R.; Atwood, Craig S.; Carlsson, Cynthia M.; Asthana, Sanjay (11 August 2015). "Cognitive Effects of Soy Isoflavones in Patients with Alzheimer's Disease". Journal of Alzheimer's Disease. 47 (4): 1009–1019. doi:10.3233/JAD-142958. ISSN 1875-8908. PMC 4657545. PMID 26401779.
  7. ↑ Dysken, Maurice W.; Sano, Mary; Asthana, Sanjay; Vertrees, Julia E.; Pallaki, Muralidhar; Llorente, Maria; Love, Susan; Schellenberg, Gerard D.; McCarten, J. Riley (1 January 2014). "Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial". JAMA. 311 (1): 33–44. doi:10.1001/jama.2013.282834. ISSN 1538-3598. PMC 4109898. PMID 24381967.
  8. ↑ Wharton, Whitney; Stein, James H.; Korcarz, Claudia; Sachs, Jane; Olson, Sandra R.; Zetterberg, Henrik; Dowling, Maritza; Ye, Shuyun; Gleason, Carey E. (1 January 2012). "The effects of ramipril in individuals at risk for Alzheimer's disease: results of a pilot clinical trial". Journal of Alzheimer's Disease. 32 (1): 147–156. doi:10.3233/JAD-2012-120763. ISSN 1875-8908. PMC 3593582. PMID 22776970.
  9. ↑ Willette, Auriel A.; Johnson, Sterling C.; Birdsill, Alex C.; Sager, Mark A.; Christian, Bradley; Baker, Laura D.; Craft, Suzanne; Oh, Jennifer; Statz, Eric (1 May 2015). "Insulin resistance predicts brain amyloid deposition in late middle-aged adults". Alzheimer's & Dementia. 11 (5): 504–510.e1. doi:10.1016/j.jalz.2014.03.011. ISSN 1552-5279. PMC 4297592. PMID 25043908.
  10. ↑ Starks, Erika J.; Patrick O'Grady, J.; Hoscheidt, Siobhan M.; Racine, Annie M.; Carlsson, Cynthia M.; Zetterberg, Henrik; Blennow, Kaj; Okonkwo, Ozioma C.; Puglielli, Luigi (30 May 2015). "Insulin Resistance is Associated with Higher Cerebrospinal Fluid Tau Levels in Asymptomatic APOEɛ4 Carriers". Journal of Alzheimer's Disease. 46 (2): 525–533. doi:10.3233/JAD-150072. ISSN 1875-8908. PMC 4583335. PMID 25812851.
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