Selenium responsive proteins within human biology, are the class of proteins sensitive to selenium, in healthy human beings, in cancer patients, in in-vivo models or in-vitro cell culture models.
The original gi accession (version) numbers have been updated to NCBI accession number and protein names updated accordingly.
| Accession Number | Common abbreviation | Protein name | Responsive in | Selenium compound | technique used | source | |
|---|---|---|---|---|---|---|---|
| Q08091 | CNN1 | Calponin-1 | TRAMP (prostate cancer mouse model) | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| NP_035656 | TAGLN | Transgelin | TRAMP (prostate cancer mouse model) | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| NP_033822 | APOA1 | Apolipoprotein A-I | TRAMP (prostate cancer mouse model) | MSeC, MseA | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| NP_038499 | ANXA4 | Annexin A4 | TRAMP (prostate cancer mouse model) | MseA | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| gi21071030 | A1BG | Alpha 1B-glycoprotein | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | |
| gi4557871 | TF | Transferrin | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | |
| gi4502501 | C4b | Complement component 4B proprotein | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | |
| NP_059086 | SEMG1 | semenogelin I | TRAMP DLP UP | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| CAA47699 | BGPG | Biliary glycoprotein | TRAMP DLP UP | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| NP_780375 | BASP1 | brain acid soluble protein 1 | TRAMP DLP UP | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| NP_031789 | Cysteine-rich protein 1 | TRAMP DLP UP | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| NP_059067 | HPX | Hemopexin | TRAMP DLP UP | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| gi7305531 | Seminal vesicle secretion 6 | TRAMP DLP UP | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| NP_780375 | DMBTL_MOUSE | putative DMBT1-like protein precursor | TRAMP DLP UP | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| gi6755212 | Proteasome (prosome, macropain) 28 subunit, α | TRAMP DLP UP | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| NP_035309 | PSAP | Prosaposin | TRAMP DLP UP | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| gi123794006 | FUSE-binding protein 2 | TRAMP DLP UP | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi84875537 | Nucleolin | TRAMP DLP UP | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi40254525 | Tropomyosin 3, gamma | TRAMP DLP UP | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| NP_032775 | NUCB1 | Nucleobindin 1 | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| gi94717635 | Progesterone receptor membrane component | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi21704156 | Caldesmon 1 | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi31980648 | ATP synthase, H+ transporting mitochondrial F1 complex β | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi10946574 | Creatine kinase, brain | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi94367355 | Similar to 60S ribosomal protein L5 | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi31981520 | Pancreatic ribonuclease | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6754084 | Glutathione S-transferase, mu 1 | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6680121 | Glutathione S-transferase, μ 2 | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi31981302 | Annexin A6 | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6678740 | Lumican | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi94403723 | Similar to Heat shock 70-kDa protein 1B (HSP70.1) | TRAMP DLP DOWN | MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi89574165 | Succinate dehydrogenase complex subunit A | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi70778915 | Moesin | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6679567 | Polymerase I and transcript release factor | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi31791059 | Activated leukocyte cell adhesion molecule | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi76779293 | Keratin 8 | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6671549 | Peroxiredoxin 6 | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6680836 | Calreticulin | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| NP_808579 | TGM4 | protein-glutamine gamma-glutamyltransferase 4 | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | |
| gi8567372 | Probasin | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi2506545 | 78-kDa glucose-regulated protein precursor (GRP 78) | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi7643979 | 170-kDa glucose regulated protein GRP170 | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi31542563 | DnaJ (Hsp40) homolog, subfamily C, member 3 | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi71774133 | Peptidylprolyl isomerase B (PPI) | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi130232 | Protein disulfide isomerase b family, ERp57 subfamily | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi129729 | Protein disulfide isomerase ERp59 | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi86198316 | Protein disulfide isomerase associated 4 | TRAMP DLP DOWN | MSeA | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi58037267 | Protein disulfide isomerase-associated 6 | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6753010 | Anterior gradient 2 | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi42794267 | Experimental autoimmune prostatitis antigen 2 | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi31543942 | Vinculin | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi94387119 | PREDICTED: similar to heat shock protein 8 | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6752952 | Actin, γ2, smooth muscle, enteric | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi94381948 | PREDICTED: similar to Fc fragment of IgG binding protein | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi6754482 | Keratin complex 1, acidic, gene 18 | TRAMP DLP DOWN | MSeA, MSeC | iTRAQ LC-MS/MS | Zhang 2010 [1] | ||
| gi5031777 | isocitrate dehydrogenase | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | ||
| NP_005134 | HP | Haptoglobin isoform 1 preproprotein | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | |
| gi42716297 | CLU | Clusterin isoform 1 | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | |
| gi17318569 | Keratin 1 | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | ||
| gi4507725 | Transthyretin | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | ||
| gi21361198 | AAT | Alpha-1 antitrypsin | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | |
| gi4557287 | Angiotensin precursor | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] | ||
| gi4502027 | Albumin precursor | Healthy Human blood serum | Selenium enriched yeast | 2D DIGE LC-MS/MS | Sinha 2010 [2] |
References
- 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 Zhang, J.; Wang, L.; Anderson, L. B.; Witthuhn, B.; Xu, Y.; Lu, J. (2010). "Proteomic Profiling of Potential Molecular Targets of Methyl-Selenium Compounds in the Transgenic Adenocarcinoma of Mouse Prostate Model". Cancer Prevention Research. 3 (8): 994–1006. doi:10.1158/1940-6207.CAPR-09-0261. PMID 20647336.
- 1 2 3 4 5 6 7 8 9 10 11 Sinha, R.; Sinha, I.; Facompre, N.; Russell, S.; Somiari, R.; Richie Jr, J.; El-Bayoumy, K. (2010). "Selenium responsive proteins in sera of selenium-enriched yeast supplemented healthy African American and Caucasian men". Cancer Epidemiology, Biomarkers & Prevention. 19 (9): 2332–2340. doi:10.1158/1055-9965.EPI-10-0253. PMC 3326597. PMID 20643827.
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