Single Scan Dynamic Molecular Imaging Technique is a positron emission tomography (PET) based neuroimaging technique that allows detection of dopamine released in the brain during a cognitive or behavioral processing. The technique was developed by a psychiatry resident Rajendra Badgaiyan and his colleagues at Massachusetts General Hospital Boston.. The technique has been used to detect dopamine released during cognitive, behavioral and emotional tasks by a number of investigators.[1][2][3][4][5][6][7][8][9][10] This technique has for the first time allowed scientists to detect changes in the concentration of neurotransmitters released acutely during task performance. It expanded the scope of neuroimaging studies by allowing detection of neurochemical changes associated with the brain processing.

References

  1. ↑ Badgaiyan RD. Imaging dopamine neurotransmission in live human brain. Prog Brain Res. 2014;211:165-182.
  2. ↑ Badgaiyan RD. Detection of dopamine neurotransmission in "real time". Frontiers in neuroscience. 2013;7:125.
  3. ↑ Badgaiyan RD, Wack D. Evidence of dopaminergic processing of executive inhibition. PLoS One. 2011;6(12):e28075.
  4. ↑ Badgaiyan RD. Neurotransmitter Imaging: Current Status and Challenges. Current Medical Imaging Reviews. 2011;7:96-98.
  5. ↑ Badgaiyan RD. Dopamine is released in the striatum during human emotional processing. NeuroReport. 2010;21:1172-1176.
  6. ↑ Badgaiyan RD, Fischman AJ, Alpert NM. Dopamine release during human emotional processing. Neuroimage. 2009;47(4):2041-2045.
  7. ↑ Badgaiyan RD, Fischman AJ, Alpert NM. Striatal dopamine release in sequential learning. NeuroImage. 2007;38(3):549-556.
  8. ↑ Badgaiyan RD, Fischman AJ, Alpert NM. Striatal dopamine release during unrewarded motor task in human volunteers. NeuroReport. 2003;14(11):1421-1424.
  9. ↑ Christian B, Lehrer D, Shi B, et al. Measuring dopamine neuromodulation in the thalamus: using [F-18]fallypride PET to study dopamine release during a spatial attention task. Neuroimage. 2006;31(1):139-152
  10. ↑ Backman L, Nyberg L, Soveri A, et al. Effects of working-memory training on striatal dopamine release. Science. 2011;333(6043):718.

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