Suppression of tumorigenicity 2 [1] is a gene that in humans is located on chromosome 11p14.3-p12. This region (ST2; GeneID: 6761)[2] on chromosome 11 represents a putative locus that is associated with various forms of cancer.

It has been confused in the published literature [3] with the IL1RL1 gene (GeneID: 9173),[4] which has the alias ST2, but is located on chromosome 2 and encodes a member of the interleukin 1 receptor family, IL1RL1.

References

  1. ↑ "NCBI gene - ST2".
  2. ↑ "ST2 Gene". GeneCards.
  3. ↑ Griesenauer, Brad; Paczesny, Sophie (24 April 2017). "The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases". Frontiers in Immunology. Frontiers. 8: 475. doi:10.3389/fimmu.2017.00475. PMC 5402045. PMID 28484466.
  4. ↑ "IL1RL1 Gene". Frontiers.
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