TNPO2
Identifiers
AliasesTNPO2, IPO3, KPNB2B, TRN2, transportin 2
External IDsOMIM: 603002 MGI: 2384849 HomoloGene: 8381 GeneCards: TNPO2
Orthologs
SpeciesHumanMouse
Entrez

30000

212999

Ensembl

ENSG00000105576

ENSMUSG00000031691

UniProt

O14787

Q99LG2

RefSeq (mRNA)

NM_013433
NM_001136195
NM_001136196

RefSeq (protein)
Location (UCSC)Chr 19: 12.7 – 12.72 MbChr 8: 85.76 – 85.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transportin-2 is a protein that in humans is encoded by the TNPO2 gene.[5][6][7]

Interactions

TNPO2 has been shown to interact with NXF1,[6] NUP98[8] and Ran (biology).[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000105576 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031691 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G (September 1997). "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins". The Journal of Cell Biology. 138 (6): 1181–92. doi:10.1083/jcb.138.6.1181. PMC 2132560. PMID 9298975.
  6. 1 2 3 Shamsher MK, Ploski J, Radu A (October 2002). "Karyopherin beta 2B participates in mRNA export from the nucleus". Proceedings of the National Academy of Sciences of the United States of America. 99 (22): 14195–9. Bibcode:2002PNAS...9914195S. doi:10.1073/pnas.212518199. PMC 137860. PMID 12384575.
  7. "Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)".
  8. Fontoura BM, Blobel G, Yaseen NR (October 2000). "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import". The Journal of Biological Chemistry. 275 (40): 31289–96. doi:10.1074/jbc.M004651200. PMID 10875935.

Further reading


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