TP53INP1
Identifiers
AliasesTP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1, tumor protein p53 inducible nuclear protein 1
External IDsOMIM: 606185 MGI: 1926609 HomoloGene: 11065 GeneCards: TP53INP1
Orthologs
SpeciesHumanMouse
Entrez

94241

60599

Ensembl

ENSG00000164938

ENSMUSG00000028211

UniProt

Q96A56

Q9QXE4

RefSeq (mRNA)

NM_001135733
NM_033285

NM_001199105
NM_021897

RefSeq (protein)

NP_001129205
NP_150601

NP_001186034
NP_068697

Location (UCSC)Chr 8: 94.93 – 94.95 MbChr 4: 11.16 – 11.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tumor protein p53-inducible nuclear protein 1 is a protein that in humans is encoded by the TP53INP1 gene.[5][6][7] In mice this protein is also called TRP53INP1 and is encoded by the Trp53inp1 gene. The protein is also referred to as SIP or "stress inducible protein"


Interactions

TP53INP1 has been shown to interact with HIPK2[8] and p53.[5][8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000164938 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028211 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Okamura S, Arakawa H, Tanaka T, Nakanishi H, Ng CC, Taya Y, Monden M, Nakamura Y (Aug 2001). "p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis". Mol Cell. 8 (1): 85–94. doi:10.1016/S1097-2765(01)00284-2. PMID 11511362.
  6. Nowak J, Tomasini R, Mattei MG, Azizi Samir LA, Dagorn JC, Dusetti N, Iovanna JL, Pebusque MJ (Nov 2002). "Assignment of tumor protein p53 induced nuclear protein 1 (TP53INP1) gene to human chromosome band 8q22 by in situ hybridization". Cytogenet Genome Res. 97 (1–2): 140E. doi:10.1159/000064049. PMID 12438758.
  7. "Entrez Gene: TP53INP1 tumor protein p53 inducible nuclear protein 1".
  8. 1 2 Tomasini, Richard; Samir Amina Azizi; Carrier Alice; Isnardon Daniel; Cecchinelli Barbara; Soddu Silvia; Malissen Bernard; Dagorn Jean-Charles; Iovanna Juan L; Dusetti Nelson J (Sep 2003). "TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity". J. Biol. Chem. United States. 278 (39): 37722–9. doi:10.1074/jbc.M301979200. ISSN 0021-9258. PMID 12851404.

Further reading


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