TRAF3IP3
Identifiers
AliasesTRAF3IP3, T3JAM, TRAF3 interacting protein 3
External IDsOMIM: 608255 MGI: 2441706 HomoloGene: 11885 GeneCards: TRAF3IP3
Orthologs
SpeciesHumanMouse
Entrez

80342

215243

Ensembl

ENSG00000009790

ENSMUSG00000037318

UniProt

Q9Y228

Q8C0G2

RefSeq (mRNA)

NM_001287754
NM_025228
NM_001320143
NM_001320144

NM_153137

RefSeq (protein)

NP_001274683
NP_001307072
NP_001307073
NP_079504

NP_694777

Location (UCSC)Chr 1: 209.76 – 209.78 MbChr 1: 192.86 – 192.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TRAF3-interacting JNK-activating modulator is a protein that in humans is encoded by the TRAF3IP3 gene.[5][6]

Interactions

TRAF3IP3 has been shown to interact with STRN,[7] MOBKL3,[7] STK24[7] and FAM40A.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000009790 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037318 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Dadgostar H, Doyle SE, Shahangian A, Garcia DE, Cheng G (Oct 2003). "T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1)". FEBS Letters. 553 (3): 403–7. doi:10.1016/S0014-5793(03)01072-X. PMID 14572659. S2CID 8938949.
  6. "Entrez Gene: TRAF3IP3 TRAF3 interacting protein 3".
  7. 1 2 3 4 Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Molecular & Cellular Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.

Further reading

  • Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Vasilescu J, Zweitzig DR, Denis NJ, Smith JC, Ethier M, Haines DS, Figeys D (Jan 2007). "The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells". Journal of Proteome Research. 6 (1): 298–305. CiteSeerX 10.1.1.401.4220. doi:10.1021/pr060438j. PMID 17203973.
  • Zhang C, Xie L, Cheng H, Wang Y (Feb 2007). "TRAF3 interacts with Smac/DIABLO and enhances the proapoptotic effect of Smac/DIABLO in cytoplasm". Acta Biochimica et Biophysica Sinica. 39 (2): 108–16. doi:10.1111/j.1745-7270.2007.00259.x. PMID 17277885. S2CID 19440495.
  • Ma X, Wang X, Gao X, Wang L, Lu Y, Gao P, Deng W, Yu P, Ma J, Guo J, Cheng H, Zhang C, Shi T, Ma D (Sep 2007). "Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library". Life Sciences. 81 (14): 1141–51. doi:10.1016/j.lfs.2007.08.006. PMID 17868742.
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