TRIM45 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | TRIM45, RNF99, tripartite motif containing 45 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 609318 MGI: 1918187 HomoloGene: 11865 GeneCards: TRIM45 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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tripartite motif containing 45, also known as TRIM45, is a human gene.[5]
This gene encodes a member of the tripartite motif family. The encoded protein may function as a [transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.[5]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000134253 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033233 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- 1 2 "Entrez Gene: tripartite motif containing 45". Retrieved 2011-08-30.
Further reading
- Sardiello M, Cairo S, Fontanella B, Ballabio A, Meroni G (2008). "Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties". BMC Evolutionary Biology. 8 (1): 225. Bibcode:2008BMCEE...8..225S. doi:10.1186/1471-2148-8-225. PMC 2533329. PMID 18673550.
- Wang Y, Li Y, Qi X, Yuan W, Ai J, Zhu C, Cao L, Yang H, Liu F, Wu X, Liu M (Oct 2004). "TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1". Biochemical and Biophysical Research Communications. 323 (1): 9–16. doi:10.1016/j.bbrc.2004.08.048. PMID 15351693.
- Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
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