Thomas Wilkinson King (1809 – 26 March 1847) was an English pathologist and anatomist. He has been called "the father of endocrinology" because of a landmark paper he wrote about the thyroid gland while working at Guy's Hospital.

Early life and education

King was born in 1809 and was educated in London and Paris.[1] He became a doctor like his father, who practised in Dover, and began training at Guy's Hospital as a teenager in 1824.[2] He was appointed curator of the Guy's Hospital museum, a position previously held by Thomas Hodgkin, in 1837, and three years later became a lecturer in comparative anatomy and comparative physiology.[3] He also lectured in anatomical pathology and wrote prolifically in the Guy's Hospital Reports, particularly about cancer.[1]

Career

King has been called "the father of endocrinology" because of an important paper he wrote about the thyroid gland, where he proposed the concept of internal secretion of hormones into the bloodstream.[2] The paper was published in the Guy's Hospital Reports in 1836, and fell into obscurity until it was discussed by Sir Humphry Rolleston at the Fitzpatrick Lecture in 1933.[3] His paper described in detail the anatomy of the thyroid gland and theorised that, because of the thyroid's significant vascular supply and "peculiar" fluid, the blood vessels transported the thyroid's secretions throughout the body. He also proposed that the levels of thyroid secretions would vary during the day since the gland was subjected to periodic compression during chewing and movement of the nearby oesophagus, larynx and neck muscles.[4]

Later life and death

King was one of the original Fellows of the Royal College of Surgeons of England upon its establishment in December 1843. At that time, he was living and practising at 36 Bedford Square in London. He died of tuberculosis in 1847.[3]

References

  1. 1 2 "King, Thomas Wilkinson (1809–1847)". Plarr's Lives of the Fellows. 14 June 2012. Retrieved 22 December 2018.
  2. 1 2 "Thomas Wilkinson King, Father of Endocrinology". The Journal of Nervous and Mental Disease. 85 (2): 207. February 1937. doi:10.1097/00005053-193702000-00009.
  3. 1 2 3 "Dr. T. W. King (1809–47)". Nature. 159 (4037): 365. 15 March 1947. Bibcode:1947Natur.159Q.365.. doi:10.1038/159365a0.
  4. ↑ Slater, Stefan (1 February 2011). "The discovery of thyroid replacement therapy. Part 2: The critical 19th century". Journal of the Royal Society of Medicine. 104 (2): 59–63. doi:10.1258/jrsm.2010.10k051. PMC 3031643. PMID 21282795.
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