VPS26B

VPS26B
Identifiers
Aliases	VPS26B, Pep8b, VPS26 retromer complex component B, VPS26, retromer complex component B
External IDs	OMIM: 610027 MGI: 1917656 HomoloGene: 3601 GeneCards: VPS26B
Gene location (Human)
Chr.	Chromosome 11 (human)
End	134,247,788 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	26,941,361 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; prefrontal cortex; ; Brodmann area 9; ; skin of abdomen; ; cingulate gyrus; ; right uterine tube; ; body of pancreas; ; nucleus accumbens; ; stromal cell of endometrium; ; caudate nucleus;
	Top expressed in
	ascending aorta; ; aortic valve; ; Region I of hippocampus proper; ; subiculum; ; nucleus accumbens; ; supraoptic nucleus; ; cerebellar cortex; ; barrel cortex; ; olfactory tubercle; ; cerebellar vermis;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; retromer complex; late endosome; early endosome; membrane; retromer, cargo-selective complex; endosome; cytosol; phagocytic vesicle;
Biological process	protein transport; retrograde transport, endosome to Golgi; regulation of macroautophagy; intracellular protein transport; cellular response to interferon-gamma; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	112936
	69091
	ENSG00000151502
	ENSMUSG00000031988
	Q4G0F5
	Q8C0E2
	NM_052875
	NM_178027
	NP_443107; NP_443107.1
	NP_821170
	Wikidata
View/Edit Human	View/Edit Mouse

Vacuolar protein sorting 26 homolog B (S. pombe) is a protein in humans that is encoded by the VPS26B gene. ^[5]

References

Haft CR, de la Luz Sierra M, Bafford R, Lesniak MA, Barr VA, Taylor SI (December 2000). "Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes". Mol. Biol. Cell. 11 (12): 4105–16. doi:10.1091/mbc.11.12.4105. PMC 15060. PMID 11102511.
Kerr MC, Bennetts JS, Simpson F, Thomas EC, Flegg C, Gleeson PA, Wicking C, Teasdale RD (November 2005). "A novel mammalian retromer component, Vps26B". Traffic. 6 (11): 991–1001. doi:10.1111/j.1600-0854.2005.00328.x. PMID 16190980. S2CID 31954489.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.