Webe Celine Kadima (born 1958) is an associate professor of chemistry at the State University of New York at Oswego.[1][2]

Early life

Kadima was born in Burundi and moved to the Democratic Republic of Congo when she was 4 years old.[3] She had to get the support of a government official to be included in the chemistry program at the University of Kinshasa, and after a year there she transferred to the University of Montreal, from which she graduated with a degree in chemistry.[4] Her father was a diabetic and died from complications from diabetes while she was at the University of Montreal.[5] She eventually obtained a PhD in bioanalytical chemistry from the University of Alberta.[4] In her research for it she discovered that cadmium binds within the red blood cell mostly to glutathione and to a lesser degree to hemoglobin.[4]

Career

After graduating from the University of Alberta, Kadima held several different teaching positions and eventually became a professor at the State University of New York at Oswego.[3][4] In 2004 she went back to the Congo for a sabbatical to collaborate on research projects, concentrating her research on plants used in the Congo to treat diabetes.[4] She created a nonprofit called the Bioactive Botanical Research Institute, whose mission was to investigate medicinal plants used in the Congo and to develop pharmaceutical preparations that would be affordable, useful, and safe.[4] She has also worked to create an ongoing exchange of African students with the State University of New York at Oswego.[6] In 2010 it was announced that she had received a $200,000 National Science Foundation grant for the study of how to expand the number of women in science.[7][8]

In July 1983, she published the results of her M.Sc. research on a proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes together with Rabenstein, Isab and Mohanakrishnan.[9] She was later first author on a paper looking at the stability of the cadmium-glutathione complex in hemolysed red blood cells.[10] In the Inorganica Chimica Acta she published an article about the kinetics of palladium ethylenediamine chloride in solution.[11]

Scientific publications

  • Webe Kadima and Michael Hanson: A NMR Study of the T3R3 to R6 Allosteric Transition in the Iron-substituted Insulin Hexamer. Working Paper, Jan 2017.[12]
  • Webe Kadima, Angela Nugroho, Deborah Kerwood and Phil Borer: The T- to R-Allosteric Transition in the Cadmium-substituted Insulin Hexamer. Research, Jan 2016.[12]
  • Webe Kadima: Diabetes Screening in Kinshasa, Democratic Republic of Congo. Research, Jan 2016.[12]
  • Helle Birk Olsen, Melissa R Leuenberger-Fisher, Webe Kadima, [...], Michael F Dunn: Structural signatures of the complex formed between 3-nitro-4-hydroxybenzoate and the Zn(II)-substituted R 6 insulin hexamer. Oct 2003, Protein Science.[12]
  • Webe Kadima: Role of Metal Ions in the T- To R-Allosteric Transition in the Insulin Hexamer. Nov 1999, Biochemistry.[12]
  • W. Kadima, P. Raharivelomanana and B. Bechtel: The binding of cyclic adenosine 3′, 5′ monophosphate to the insulin hexamer. Jan 1997, Protein and Peptide Letters.[12]
  • W Kadima, L Ogendal, R Bauer, [...] and P Porting: The influence of ionic strength and pH on the aggregation properties of zinc-free insulin studied by static and dynamic laser light scattering. Biopolymers. Dec 1993, Biopolymers.[12]
  • W Kadima, M Roy, R. W. K. Lee, [...], M F Dunn: Studies of the association and conformational properties of metal-free insulin in alkaline sodium chloride solutions by one- and two-dimensional 1H NMR. Jun 1992, Journal of Biological Chemistry.[12]
  • Webe Kadima, Alexander McPherson, Michael F. Dunn and Frances Jurnak: Precrystallization aggregation of insulin by dynamic light scattering and comparison with canavalin. Mar 1991, Journal of Crystal Growth.[12]
  • Webe Kadima and Dallas L. Rabenstein: A quantitative study of the complexation of cadmium in hemolyzed human erythrocytes by 1H NMR spectroscopy. Nov 1990, Journal of Inorganic Biochemistry.[12]
  • Webe Kadima and Dallas L. Rabenstein: Nuclear magnetic resonance studies of the solution chemistry of metal complexes. 26. Mixed ligand complexes of cadmium, nitrilotriacetic acid, glutathione, and related ligands. J Inorg Biochem. May 1990, Journal of Inorganic Biochemistry.[12]
  • W Kadima, A McPherson, M F Dunn and F.A. Jurnak: Characterization of precrystallization aggregation of canavalin by dynamic light scattering. Feb 1990, Biophysical Journal.[12]
  • Karl F. Houben, Webe Kadima, Melinda Roy and Michael F. Dunn: L-Serine analogs form Schiff base and quinonoidal intermediates with Escherichia coli tryptophan synthase. May 1989, Biochemistry.[12]
  • Dallas L. Rabenstein, Anvarhusein A. Isab, Webe Kadima and P Mohanakrishnan: A proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes. Aug 1983, Biochimica et Biophysica Acta.[12]
  • W. Kadima and M. Zador: Kinetics on interaction of Pd(en)Cl2 with inosine in chloride containing aqueous solutions. Jan 1983, Inorganica Chimica Acta.[12]
  • Webe Celine Kadima: NMR studies of the interaction of Cd(II) with ligands of biological interest and with red blood cells.[12]

References

  1. ↑ Faculty and staff, SUNY Oswego Chemistry, retrieved 2016-07-08.
  2. ↑ "Webe Celine Kadima". Oswego.edu. Archived from the original on 2016-07-26. Retrieved 2016-07-21.
  3. 1 2 Nicholas Lisi / The Post-Standard (2011-06-05). "Oswego State professor delves into plant use to treat diabetes". syracuse.com. Retrieved 2016-05-25.
  4. 1 2 3 4 5 6 Gates, Henry Louis Jr.; Akyeampong, Emmanuel; Niven, Steven J. (2 February 2012). "Kadima, Webe (1958–)". Dictionary of African Biography. Oxford University Press. pp. 257–258. ISBN 978-0-19-538207-5.
  5. ↑ "Student researcher helps study plants that could aid diabetics". Oswego.edu. 2011-04-06. Archived from the original on 2016-07-26. Retrieved 2016-07-21.
  6. ↑ "Fulbright Scholar Faith Maina to Educate Researchers in Kenya". Mwakilishi.com. 2016-03-15. Archived from the original on 2016-07-26. Retrieved 2016-05-25.
  7. ↑ National Science Foundation: Award Abstract #1008535: Recruiting, Retaining, and Promoting Women in STEM Fields: Preparing for an Institutional Transformation Grant.
  8. ↑ "Diversity Increases Among New Faculty, Staff, Students". The Oswegonian. 2010-10-14. Retrieved 2016-07-21.
  9. ↑ Rabenstein, Dallas L.; Isab, Anvarhusein A.; Kadima, Webe; Mohanakrishnan, P. (July 1983). "A proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 762 (4): 531–541. doi:10.1016/0167-4889(83)90057-5. PMID 6409155.
  10. ↑ Kadima, Webe; Rabenstein, Dallas L. (October 1990). "A quantitative study of the complexation of cadmium in hemolyzed human erythrocytes by1H NMR spectroscopy". Journal of Inorganic Biochemistry. 40 (2): 141–149. doi:10.1016/0162-0134(90)80047-2. PMID 2128706.
  11. ↑ Kadima, W.; Zador, M. (January 1983). "Kinetics on interaction of Pd(en)Cl2 with inosine in chloride containing aqueous solutions". Inorganica Chimica Acta. 78: 97–101. doi:10.1016/S0020-1693(00)86496-8.
  12. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 "Publications by Webe Kadima listed at ResearchGate".
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