ZBED3

ZBED3
Identifiers
Aliases	ZBED3, zinc finger BED-type containing 3
External IDs	OMIM: 615250 MGI: 1919364 HomoloGene: 12442 GeneCards: ZBED3
Gene location (Human)
Chr.	Chromosome 5 (human)
End	77,087,285 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	95,474,349 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; retinal pigment epithelium; ; smooth muscle tissue; ; left lobe of thyroid gland; ; subcutaneous adipose tissue; ; right lobe of thyroid gland; ; parotid gland; ; body of pancreas; ; left uterine tube; ; renal cortex;
	Top expressed in
	secondary oocyte; ; yolk sac; ; proximal tubule; ; ovary; ; endocardial cushion; ; abdominal wall; ; aortic valve; ; neural tube; ; ascending aorta; ; entorhinal cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; metal ion binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; membrane; cytosol;
Biological process	positive regulation of canonical Wnt signaling pathway; negative regulation of protein phosphorylation; protein stabilization; Wnt signaling pathway; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	84327
	72114
	ENSG00000132846
	ENSMUSG00000041995
	Q96IU2
	Q9D0L1
	NM_032367; NM_001329564
	NM_028106; NM_001302538; NM_001302539
	NP_001316493; NP_115743
	NP_001289467; NP_001289468; NP_082382
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger BED domain-containing protein 3 also known as axin-interacting protein is a protein in humans that is encoded by the ZBED3 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000132846 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041995 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Zinc finger, BED-type containing 3".

Hayward A, Ghazal A, Andersson G, Andersson L, Jern P (2013). Robinson-Rechavi M (ed.). "ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions". PLOS ONE. 8 (3): e59940. Bibcode:2013PLoSO...859940H. doi:10.1371/journal.pone.0059940. PMC 3606216. PMID 23533661.
de Miguel-Yanes JM, Shrader P, Pencina MJ, Fox CS, Manning AK, Grant RW, Dupuis J, Florez JC, D'Agostino RB, Cupples LA, Meigs JB (Jan 2011). "Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms" (PDF). Diabetes Care. 34 (1): 121–5. doi:10.2337/dc10-1265. PMC 3005447. PMID 20889853.
Chen T, Li M, Ding Y, Zhang LS, Xi Y, Pan WJ, Tao DL, Wang JY, Li L (Mar 2009). "Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling". The Journal of Biological Chemistry. 284 (11): 6683–9. doi:10.1074/jbc.M807753200. PMC 2652294. PMID 19141611.
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, et al. (Jul 2010). "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis". Nature Genetics. 42 (7): 579–89. doi:10.1038/ng.609. PMC 3080658. PMID 20581827.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000132846 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041995 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Zinc finger, BED-type containing 3".

[1]

[2]

[3]

[4]

[5]

References

Further reading