二甲啡烷

二甲啡烷（英語：或，全称3,17-二甲基吗啡烷，，商品名Astomin、Dastosirr或Tusben）分子式C18H25N，是一种吗啡喃衍生物，可用作止咳藥。[1][2][3][4]

二甲啡烷
臨床資料
商品名Astomin, Datosin, Gentus
AHFS/Drugs.com国际药品名称
ATC碼
识别
  • (4bS,8aS,9S)-3,11-Dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene
CAS号36309-01-0  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard100.048.134
化学
化学式C18H25N
摩尔质量255.41 g·mol−1
3D模型（JSmol）
  • CC1=CC2=C(C[C@@H]3N(CC[C@@]42CCCC[C@H]34)C)C=C1
  • InChI=1S/C18H25N/c1-13-6-7-14-12-17-15-5-3-4-8-18(15,16(14)11-13)9-10-19(17)2/h6-7,11,15,17H,3-5,8-10,12H2,1-2H3/t15-,17+,18+/m1/s1 checkY
  • Key:KBEZZLAAKIIPFK-NJAFHUGGSA-N checkY

参考文献
  1. Elks J. . Springer. 14 November 2014: 427–. ISBN 978-1-4757-2085-3.
  2. Bruera E, Higginson I, von Gunten CF, Morita T. . CRC Press. 15 January 2015: 677–. ISBN 978-1-4441-3526-8.
  3. Ida H. . Clinical Therapeutics. 1997, 19 (2): 215–31. PMID 9152562. doi:10.1016/S0149-2918(97)80111-7.
  4. Armstrong LL, Goldman MP. . Lexi-Comp. 1 January 2005. ISBN 978-1-59195-110-0.
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