再攝取抑制劑

再攝取抑制劑(英語:reuptake inhibitorRI)是一種再攝取調節劑,它可抑制由細胞膜轉運體中介的神經傳導物再攝取,進而增加胞膜外神經傳導物的濃度。達成更多神經傳導. 數種藥物藉由再吸收抑制達到心理生理上的作用,包括各式抗憂鬱劑及興奮劑。[1]

多數已知的再吸收抑制劑影響單胺神經傳導物血清素去甲肾上腺素腎上腺素)及多巴胺[1] 但也有不少藥品及研究用化合物作用於其他神经递质,例如穀氨酸[2]GABA[3]甘胺酸[4]腺苷[5]胆碱乙酰胆碱前驅物[6]大麻素[7]

参考文献

  1. Iversen L. (2006).
  2. West AR, Galloway MP (1997).
  3. Pollack MH, Roy-Byrne PP, Van Ameringen M, Snyder H, Brown C, Ondrasik J, Rickels K (2005).
  4. Alberati D, Moreau JL, Lengyel J, et al.
  5. Boissard CG, Gribkoff VK (1993).
  6. Barkhimer TV, Kirchhoff JR, Hudson RA, Messer WS (November 2002). <3699::AID-ELPS3699>3.0.
  7. Costa B, Siniscalco D, Trovato AE, Comelli F, Sotgiu ML, Colleoni M, Maione S, Rossi F, Giagnoni G (2006).
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