南天竹啡碱

**南天竹啡碱**
臨床資料
ATC碼	未分配;
识别
	IUPAC命名法 (S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-benzo[de][1,3]benzodioxolo[5,6-g]quinoline; ;
CAS号	2565-01-7
PubChem CID	197001;
ChemSpider	170619 ;
UNII	XE0AU8C122;
ChEMBL	ChEMBL467094 ;
CompTox Dashboard (EPA)	DTXSID70180343 ;
化学
化学式	C20H21NO4
摩尔质量	339.39 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC5=C(C=C43)OCO5)OC)OC;
	InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1 ; Key:WSVWKHTVFGTTKJ-AWEZNQCLSA-N ;

南天竹啡碱（英语：Nantenine）是一种在南天竹[1]和一些紫堇属植物中发现的生物碱。[2]它是α1-肾上腺素能受体[3]和血清素5-HT_2A受体的拮抗剂，[4]可阻断MDMA对动物的行为和生理作用。[5]

参见

Shoji N, Umeyama A, Takemoto T, Ohizumi Y. . Journal of Pharmaceutical Sciences. April 1984, 73 (4): 568–70. PMID 6726648. doi:10.1002/jps.2600730435.
Kiryakov HG, Iskrenova E, Daskalova E, Kuzmanov B, Evstatieva L. . Planta Medica. March 1982, 44 (3): 168–70. PMID 17402105. doi:10.1055/s-2007-971432.
Indra B, Matsunaga K, Hoshino O, Suzuki M, Ogasawara H, Ohizumi Y. . European Journal of Pharmacology. February 2002, 437 (3): 173–8. PMID 11890906. doi:10.1016/S0014-2999(02)01303-1.
Chaudhary S, Pecic S, Legendre O, Navarro HA, Harding WW. . Bioorganic & Medicinal Chemistry Letters. May 2009, 19 (9): 2530–2. PMC 2677726 . PMID 19328689. doi:10.1016/j.bmcl.2009.03.048.
Fantegrossi WE, Kiessel CL, Leach PT, Van Martin C, Karabenick RL, Chen X, Ohizumi Y, Ullrich T, Rice KC, Woods JH. . Psychopharmacology. May 2004, 173 (3–4): 270–7. PMID 14740148. S2CID 8425621. doi:10.1007/s00213-003-1741-2. hdl:2027.42/46360 .

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