卤米松

卤米松是一种皮質類固醇,可用于治疗银屑病[1]以及非感染性急性湿疹皮炎类皮肤病[2]

卤米松
臨床資料
其他名稱(6S,8S,9R,10S,11S,13S,16R,17R)-2-chloro-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxy-acetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
AHFS/Drugs.com国际药品名称
ATC碼
识别
  • (6α,11β,16α)-2-chloro-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS号50629-82-8  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.051.496
化学
化学式C22H27ClF2O5
摩尔质量444.896 g/mol
3D模型(JSmol
  • O=C(CO)[C@]3(O)[C@]2(C[C@H](O)[C@]4(F)[C@@]/1(\C(=C/C(=O)C(\Cl)=C\1)[C@@H](F)C[C@H]4[C@@H]2C[C@H]3C)C)C
  • InChI=1S/C22H27ClF2O5/c1-10-4-11-12-5-15(24)13-6-16(27)14(23)7-19(13,2)21(12,25)17(28)8-20(11,3)22(10,30)18(29)9-26/h6-7,10-12,15,17,26,28,30H,4-5,8-9H2,1-3H3/t10-,11+,12+,15+,17+,19+,20+,21+,22+/m1/s1 ☒N
  • Key:GGXMRPUKBWXVHE-MIHLVHIWSA-N ☒N

参考文献

  1. Galbiati, G; Bonfacini, V; Candiani, F. . The Journal of international medical research. 1983,. 11 Suppl 1: 31–3. PMID 6339290.
  2. Yawalkar, SJ; MacArol, V; Montanari, C. . The Journal of international medical research. 1983,. 11 Suppl 1: 1–7. PMID 6339286.
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