庚酸雄甾醇酮

庚酸雄甾醇酮(英语:Androstanolone enanthate),也称为庚酸雄诺龙庚酸二氢睾酮,是一种合成的雄激素合成代谢类固醇二氢睾酮酯。[1][2]它用作注射剂,并作为雄甾醇酮二氢睾酮)的前体药物。该药物已被研究并发现可有效治疗男孩和成年男性的男性乳房发育症[3][4][5]已对庚酸雄甾醇酮的药理学进行了研究。[6][7]

庚酸雄甾醇酮
臨床資料
商品名Anaboleen Depot
其他名稱Stanolone enanthate; Dihydrotestosterone enanthate; DHT enanthate; Dihydrotestosterone heptanoate; DHTH; 5α-Androstan-17β-ol-3-one 17β-heptanoate
给药途径Intramuscular injection
藥物類別Androgen; Anabolic steroid; Androgen ester
识别
  • [(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] heptanoate
CAS号33776-88-4
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
化学
化学式C26H42O3
摩尔质量402.62 g·mol−1
3D模型(JSmol
  • CCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C
  • InChI=1S/C26H42O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h18,20-23H,4-17H2,1-3H3/t18-,20-,21-,22-,23-,25-,26-/m0/s1
  • Key:DDYHAKNCTGGYOK-LVYWIKMTSA-N

参见

  • 雄激素酯列表

参考资料

  1. J. Elks. . Springer. 14 November 2014: 640–. ISBN 978-1-4757-2085-3.
  2. I.K. Morton; Judith M. Hall. . Springer Science & Business Media. 6 December 2012: 261–. ISBN 978-94-011-4439-1.
  3. Swerdloff, Ronald S.; Wang, Christina. . Baillière's Clinical Endocrinology and Metabolism. 1998, 12 (3): 501–506. ISSN 0950-351X. PMID 10332569. doi:10.1016/S0950-351X(98)80267-X.
  4. Eberle AJ, Sparrow JT, Keenan BS. . J. Pediatr. 1986, 109 (1): 144–9. PMID 3088241. doi:10.1016/s0022-3476(86)80596-0.
  5. Swerdloff, Ronald S.; Dudley, Robert E.; Page, Stephanie T.; Wang, Christina; Salameh, Wael A. . Endocrine Reviews. 2017, 38 (3): 220–254. ISSN 0163-769X. PMC 6459338可免费查阅. PMID 28472278. doi:10.1210/er.2016-1067可免费查阅.
  6. Keenan, Bruce S.; Eberle, Andrea J.; Sparrow, James T.; Greger, Nancy G.; Panko, Walter B. . The Journal of Clinical Endocrinology & Metabolism. 1987, 64 (3): 557–562. ISSN 0021-972X. PMID 3546348. doi:10.1210/jcem-64-3-557.
  7. Coutts SB, Kicman AT, Hurst DT, Cowan DA. . Clin. Chem. November 1997, 43 (11): 2091–8. PMID 9365393. doi:10.1093/clinchem/43.11.2091可免费查阅.
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