志賀毒素

志賀毒素英語:,簡寫為STX)是由志賀氏菌屬等细菌所分泌的外毒素,由α和β亚基組合而成,位于细菌基因组原噬菌体[1],这一蛋白最早由志賀潔发现[2]。过去常把大腸桿菌分泌的志賀毒素称为志賀样毒素(,SLT),但现在这一词已不常用,能产生志賀毒素的大腸桿菌有O157:H7型O104:H4型[3][4][5]

痢疾志贺氏菌S. dysenteriae)志賀毒素的飄帶圖,源自PDB 1R4Q数据库
志賀样毒素alpha亚基
鑑定
標誌SLT_alpha
InterProIPR016331
SCOP1r4q / SUPFAM
志賀样毒素beta亚基
鑑定
標誌SLT_beta
PfamPF02258旧版
InterProIPR003189
SCOP2bos / SUPFAM
TCDB1.C.54

参考文献

  1. Friedman D; Court D. . Current Opinion in Microbiology. 2001, 4 (2): 201–7. PMID 11282477. doi:10.1016/S1369-5274(00)00189-2.
  2. Trofa, Andrew F.; Ueno-Olsen, Hannah; Oiwa, Ruiko; Yoshikawa, Masanosuke. . Clinical Infectious Diseases. 1999-11-01, 29 (5): 1303–1306. ISSN 1058-4838. PMID 10524979. doi:10.1086/313437可免费查阅 (英语).
  3. Zhu Q; Li L; Guo Z; Yang R. . Chin. Med. J. June 2002, 115 (6): 815–8. PMID 12123543.
  4. Beutin L. . Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health. 2006, 53 (7): 299–305. PMID 16930272. doi:10.1111/j.1439-0450.2006.00968.x.
  5. Spears; et al. . FEMS Microbiology Letters. 2006, 255 (2): 187–202. PMID 16448495. doi:10.1111/j.1574-6968.2006.00119.x可免费查阅.
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