扎莫特罗

沙莫特罗（INN：xamoterol）是一种强心剂。它通过与β1肾上腺素受体结合发挥作用。它是第三代肾上腺素β受体部分激动剂[1]。它在休息时提供心脏刺激，但在运动时充当阻滞剂[2]。

扎莫特罗
臨床資料
ATC碼
识别
  • (RS)-N-(2-{[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)morpholine-4-carboxamide
CAS号81801-12-9  ☒N
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
化学
化学式C16H25N3O5
摩尔质量339.39 g·mol−1
3D模型（JSmol）
  • O=C(NCCNCC(O)COc1ccc(O)cc1)N2CCOCC2
  • InChI=1S/C16H25N3O5/c20-13-1-3-15(4-2-13)24-12-14(21)11-17-5-6-18-16(22)19-7-9-23-10-8-19/h1-4,14,17,20-21H,5-12H2,(H,18,22) checkY
  • Key:DXPOSRCHIDYWHW-UHFFFAOYSA-N checkY

参考资料
  1. Marlow HF. . British Journal of Clinical Pharmacology. 1989, 28 (Suppl 1): 23S–30S. PMC 1379873 可免费查阅. PMID 2572251. doi:10.1111/j.1365-2125.1989.tb03570.x.
  2. Rang HP, Dale MM, Ritter JM, Moore PK. 5th. Edinburgh; New York: Churchill Livingstone. 1999: 163. ISBN 0443059748.
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