普沙托韦

**普沙托韦**
臨床資料
商品名	Presatovir
法律規範狀態
法律規範	美：Investigational New Drug;
识别
	IUPAC命名法 N-[2-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-4-chlorophenyl]methanesulfonamide; ;
CAS号	1353625-73-6
PubChem CID	58029842;
化学
化学式	C24H30ClN7O3S
摩尔质量	532.1
3D模型（JSmol）	交互式图像;
	SMILES CC1=CN2C(=CC(=N2)[C@@H]3CCCCN3C(=O)C4=C(C=CC(=C4)Cl)NS(=O)(=O)C)N=C1N5CC[C@@H](C5)N;
	InChI InChI=1S/C24H30ClN7O3S/c1-15-13-32-22(27-23(15)30-10-8-17(26)14-30)12-20(28-32)21-5-3-4-9-31(21)24(33)18-11-16(25)6-7-19(18)29-36(2,34)35/h6-7,11-13,17,21,29H,3-5,8-10,14,26H2,1-2H3/t17-,21-/m0/s1; Key:GOFXWTVKPWJNGD-UWJYYQICSA-N;

普沙托韦（GS-5806，化学式C₂₄H₃₀ClN₇O₃S）是一种抗病毒药，被开发用于治疗呼吸道合胞病毒感染。它作为一种融合抑制剂，在II期临床试验中显示出较好的疗效。[1][2]

参见

Marty FM, Chemaly RF, Mullane KM, Lee DG, Hirsch HH, Small CB, et al. . Clinical Infectious Diseases. December 2019. PMID 31915807. doi:10.1093/cid/ciz1167.
Stray K, Perron M, Porter DP, Anderson F, Lewis SA, Perry J, et al. . The Journal of Infectious Diseases. January 2020. PMID 31971597. doi:10.1093/infdis/jiaa028.

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