氧雄龙

氧雄龙英語:)是一种雄激素同化類固醇(AAS)药物,具有增重效应,能减缓皮質類固醇造成的异化作用[4],分子式C19H30O3

氧雄龙
臨床資料
商品名Oxandrin, Anavar, others
其他名稱Var; CB-8075; NSC-67068; SC-11585; Protivar; 17α-Methyl-2-oxa-4,5α-dihydrotestosterone; 17α-Methyl-2-oxa-DHT; 17α-Methyl-2-oxa-5α-androstan-17β-ol-3-one
AHFS/Drugs.comMonograph
MedlinePlusa604024
懷孕分級
  • X
给药途径By mouth
藥物類別Androgen; Anabolic steroid
ATC碼
法律規範狀態
法律規範
藥物動力學數據
生物利用度97%[1]
血漿蛋白結合率94–97%[1]
药物代谢Kidneys (primarily), liver[2][1]
生物半衰期Adults: 9.4–10.4 hours[1][3]
Elderly: 13.3 hours[3]
排泄途徑Urine: 28% (unchanged)[3]
Feces: 3%[3]
识别
  • (1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one
CAS号53-39-4  checkY
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.158
化学
化学式C19H30O3
摩尔质量306.45 g·mol−1
3D模型(JSmol
  • C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(COC(=O)C4)C
  • InChI=1S/C19H30O3/c1-17-11-22-16(20)10-12(17)4-5-13-14(17)6-8-18(2)15(13)7-9-19(18,3)21/h12-15,21H,4-11H2,1-3H3/t12-,13+,14-,15-,17-,18-,19-/m0/s1 checkY
  • Key:QSLJIVKCVHQPLV-PEMPUTJUSA-N checkY

参考文献

  1. Ashraf Mozayani; Lionel Raymon. . Springer Science & Business Media. 15 October 2003: 513– [2021-07-25]. ISBN 978-1-59259-654-6. (原始内容存档于2019-12-15).
  2. R.A.S Hemat. . Urotext. 2 March 2003: 108– [2021-07-25]. ISBN 978-1-903737-08-8. (原始内容存档于2021-07-25).
  3. Miller JT, Btaiche IF. (PDF). Pharmacotherapy. February 2009, 29 (2): 213–26 [2021-07-25]. PMID 19170590. S2CID 25780591. doi:10.1592/phco.29.2.213. hdl:2027.42/90285可免费查阅. (原始内容存档 (PDF)于2021-08-29).
  4. William Llewellyn. . Molecular Nutrition Llc. 2011: 342–352 [2021-07-25]. ISBN 978-0-9828280-1-4. (原始内容存档于2021-07-25).

外部链接

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