泊马度胺

**泊马度胺**
臨床資料
商品名	Pomalyst, Imnovid
AHFS/Drugs.com	Monograph
MedlinePlus	a613030
核准狀況	歐 EMA: yes; 美 DailyMed: Pomalidomide;
懷孕分級	澳: X (高风险) [1];
给药途径	By mouth
ATC碼	L04AX06 (WHO) ;
法律規範狀態
法律規範	澳：限医生处方（S4）[2][3]; 加：处方药（℞-only）[4]; 歐：Rx-only[5]; 英：处方药（℞-only） (POM)[6]; 美：处方药（℞-only）[7]; Rx-to 3Donly;
藥物動力學數據
生物利用度	73% (at least)[8]
血漿蛋白結合率	12–44%
药物代谢	Liver (mostly CYP1A2- and CYP3A4-mediated; some minor contributions by CYP2C19 and CYP2D6)
生物半衰期	7.5 hours
排泄途徑	Urine (73%), faeces (15%)
识别
	IUPAC命名法 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione; ;
CAS号	19171-19-8
PubChem CID	134780;
IUPHAR/BPS	7348;
DrugBank	DB08910 ;
ChemSpider	118785 ;
UNII	D2UX06XLB5;
KEGG	D08976 ;
ChEMBL	ChEMBL43452 ;
CompTox Dashboard (EPA)	DTXSID40893458 ;
ECHA InfoCard	100.232.884
化学
化学式	C13H11N3O4
摩尔质量	273.25 g·mol−1
3D模型（JSmol）	交互式图像;
手性	Racemic mixture
	SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N;
	InChI InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18) ; Key:UVSMNLNDYGZFPF-UHFFFAOYSA-N ;

泊马度胺（英語：，商品名有Pomalyst、Imnovid）是一种含氮有机化合物，化学式为C₁₃H₁₁N₃O₄，可作为化疗药物[5]，用于治疗多發性骨髓瘤和AIDS相关的卡波西肉瘤[7]。

参考文献

. Drugs.com. 14 May 2020 [21 September 2020]. （原始内容存档于25 January 2021）.
. Therapeutic Goods Administration (TGA). 5 December 2022 [9 April 2023]. （原始内容存档于18 March 2023）.
. Therapeutic Goods Administration (TGA). 21 June 2022 [10 April 2023]. （原始内容存档于10 April 2023）.
.
. European Medicines Agency (EMA). 17 September 2018 [21 September 2020]. （原始内容存档于27 October 2020）. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
. (emc). 16 June 2020 [21 September 2020]. （原始内容存档于26 October 2020）.
. DailyMed. 7 December 2017 [21 September 2020]. （原始内容存档于20 October 2020）.
(PDF). Celgene Europe Ltd.: 22. [21 August 2016]. （原始内容存档 (PDF)于27 June 2016）.

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