网球花胺
网球花胺是一种来自石蒜科的具有文殊兰碱结构的生物鹼，化学式为C17H19NO4。[1](+)-网球花胺可以D-葡萄糖为原料经多步反应合成得到。[2]它在吡啶存在下和乙酸酐反应，可以得到11-乙酰基网球花胺。[3]
| 网球花胺 | |
|---|---|
 | |
| IUPAC名 3β-Methoxy-1,2-didehydro-5α,13α,19α-crinan-11β-ol | |
| 系统名 (3S,4aS,5S,11bS,12R)-3-Methoxy-4,4a-dihydro-3H,6H,9H-5,11b-ethano[1,3]dioxolo[4,5-j]phenanthridin-12-ol | |
| 别名 | Hemanthamine |
| 识别 | |
| CAS号 | 466-75-1 |
| PubChem | 441593 |
| SMILES |
|
| KEGG | C08527 |
| 性质 | |
| 化学式 | C17H19NO4 |
| 摩尔质量 | 301.34 g·mol−1 |
| 熔点 | 200~202 °C |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
参考文献
- . MeSH Database. National Center for Biotechnology Information. [2024-02-06]. （原始内容存档于2024-02-06）.
- Total synthesis of Amaryllidaceae alkaloids, (+)-vittatine and (+)-haemanthamine, starting from d-glucose. Tetrahedron, 2007. doi:10.1016/j.tet.2007.05.041.
- Synthesis and antimalarial activity of new haemanthamine-type derivatives. Bioorganic & Medicinal Chemistry. 2012. doi:10.1016/j.bmc.2012.07.036.
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