转化生长因子-β超家族
转化生长因子-β超家族(transforming growth factor beta superfamily,TGF-β superfamily)是生长因子中的一大家族。分为多个亚家族[2][3][4][5]:
- 转化生长因子-β亚家族,包括:转化生长因子-β1、转化生长因子-β2、转化生长因子-β3
- DVR(decapentaplegic Vg-related)亚家族,包括:
- 骨塑型蛋白(BMPs),如:骨塑型蛋白2、骨塑型蛋白8、骨塑型蛋白10、骨塑型蛋白15
- 生長分化因子(GDFs),如:生长分化因子1-3、生长分化因子5-11、生长分化因子15
- 激活素与抑制素,如:激活素A、激活素B、抑制素A、抑制素B
- 其他,如:Nodal[6]
Transforming growth factor beta like domain | |||||||||||
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人类的转化生长因子-β2的结构.[1] | |||||||||||
鑑定 | |||||||||||
標誌 | TGF_beta | ||||||||||
Pfam | PF00019(旧版) | ||||||||||
InterPro | IPR001839 | ||||||||||
PROSITE | PDOC00223 | ||||||||||
SCOP | 1tfg / SUPFAM | ||||||||||
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参看
- 转化生长因子-β
- 生長分化因子(Growth differentiation factor)
参考资料
- Schlunegger MP, Grütter MG. . Nature. July 1992, 358 (6385): 430–4. PMID 1641027. doi:10.1038/358430a0.
- Knight, P. G., & Glister, C. (2006). TGF-β superfamily members and ovarian follicle development, Reproduction, 132(2), 191-206. Retrieved Nov 18, 2022, from https://rep.bioscientifica.com/view/journals/rep/132/2/1320191.xml (页面存档备份,存于)
- Herpin A, Lelong C, Favrel P. . Dev. Comp. Immunol. May 2004, 28 (5): 461–85. PMID 15062644. doi:10.1016/j.dci.2003.09.007.
- Burt DW. . Biochem. Biophys. Res. Commun. April 1992, 184 (2): 590–5. PMID 1575734. doi:10.1016/0006-291X(92)90630-4.
- Burt DW, Law AS. (PDF). Prog. Growth Factor Res. 1994, 5 (1): 99–118 [2022-11-18]. PMID 8199356. S2CID 41326578. doi:10.1016/0955-2235(94)90020-5. hdl:20.500.11820/50fc2d69-c411-4835-9cd9-36bf4144bae4 . (原始内容存档 (PDF)于2022-11-18).
- Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR. Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads. J Biol Chem. 2001 Jan 5;276(1):656-61. doi: 10.1074/jbc.M004649200. PMID 11024047.
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