转化生长因子-β超家族

转化生长因子-β超家族(transforming growth factor beta superfamily,TGF-β superfamily)是生长因子中的一大家族。分为多个亚家族[2][3][4][5]

  • 转化生长因子-β亚家族,包括:转化生长因子-β1转化生长因子-β2转化生长因子-β3
  • DVR(decapentaplegic Vg-related)亚家族,包括:
    • 骨塑型蛋白(BMPs),如:骨塑型蛋白2骨塑型蛋白8骨塑型蛋白10骨塑型蛋白15
    • 生長分化因子(GDFs),如:生长分化因子1-3、生长分化因子5-11、生长分化因子15
  • 激活素抑制素,如:激活素A、激活素B、抑制素A、抑制素B
  • 其他,如:Nodal[6]
Transforming growth factor beta like domain
人类的转化生长因子-β2的结构.[1]
鑑定
標誌TGF_beta
PfamPF00019旧版
InterProIPR001839
PROSITEPDOC00223
SCOP1tfg / SUPFAM

参看

参考资料

  1. Schlunegger MP, Grütter MG. . Nature. July 1992, 358 (6385): 430–4. PMID 1641027. doi:10.1038/358430a0.
  2. Knight, P. G., & Glister, C. (2006). TGF-β superfamily members and ovarian follicle development, Reproduction, 132(2), 191-206. Retrieved Nov 18, 2022, from https://rep.bioscientifica.com/view/journals/rep/132/2/1320191.xml 页面存档备份,存于
  3. Herpin A, Lelong C, Favrel P. . Dev. Comp. Immunol. May 2004, 28 (5): 461–85. PMID 15062644. doi:10.1016/j.dci.2003.09.007.
  4. Burt DW. . Biochem. Biophys. Res. Commun. April 1992, 184 (2): 590–5. PMID 1575734. doi:10.1016/0006-291X(92)90630-4.
  5. Burt DW, Law AS. (PDF). Prog. Growth Factor Res. 1994, 5 (1): 99–118 [2022-11-18]. PMID 8199356. S2CID 41326578. doi:10.1016/0955-2235(94)90020-5. hdl:20.500.11820/50fc2d69-c411-4835-9cd9-36bf4144bae4可免费查阅. (原始内容存档 (PDF)于2022-11-18).
  6. Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR. Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads. J Biol Chem. 2001 Jan 5;276(1):656-61. doi: 10.1074/jbc.M004649200. PMID 11024047.
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