醇脫氫酶
醇脫氫酶(英語:,縮寫ADH, EC 1.1.1.1 (页面存档备份,存于)),是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下两种酶促反应:
醇脱氢酶 | |||||||||
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人源ADH5二聚体的蛋白质晶体结构[1] | |||||||||
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识别码 | |||||||||
EC編號 | 1.1.1.1 | ||||||||
CAS号 | 9031-72-5 | ||||||||
数据库 | |||||||||
IntEnz | IntEnz浏览 | ||||||||
BRENDA | BRENDA入口 | ||||||||
ExPASy | NiceZyme浏览 | ||||||||
KEGG | KEGG入口 | ||||||||
MetaCyc | 代谢路径 | ||||||||
PRIAM | 概述 | ||||||||
PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
基因本体 | AmiGO / EGO | ||||||||
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醇脱氢酶是一种锌蛋白,能作用于伯醇、仲醇和半缩醛等多种受質。这种酶氧化甲醇的能力比氧化乙醇的能力弱,可以利用這個特性解除甲醇中毒。动物细胞中的醇脱氢酶还能氧化环状化合物的二级羟基,但酵母的醇脱氢则不具有这种功能。
參考
- PDB 1m6h; Sanghani PC, Robinson H, Bosron WF, Hurley TD. . Biochemistry. September 2002, 41 (35): 10778–86. PMID 12196016. doi:10.1021/bi0257639.
外部連結
维基共享资源上的相关多媒体资源:醇脫氫酶 |
- PDBsum has links to three-dimensional structures of various alcohol dehydrogenases contained in the Protein Data Bank
- ExPASy (页面存档备份,存于) contains links to the alcohol dehydrogenase sequences in Swiss-Prot, to a Medline literature search about the enzyme, and to entries in other databases.
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