2-甲氧基雌二醇

2-甲氧基雌二醇（英語：，缩写2-ME2或2-MeO-E2）是一种雌二醇（E2）和2-羟基雌二醇（2-OHE2）的天然代謝產物，可看作是儿茶酚雌激素2-羟基雌二醇的2-O-甲基醚。2-甲氧基雌二醇是一种血管新生抑制剂[2]。

2-甲氧基雌二醇
臨床資料
其他名稱2-ME2; 2-MeO-E2; 2-MeOE2; 2-Hydroxyestradiol 2-methyl ether; 2-Methoxyestra-1,3,5(10)-triene-3,17β-diol; Panzem
识别
  • (8R,9S,13S,14S,17S)-2-Methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CAS号362-07-2  checkY
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.164.606
化学
化学式C19H26O3
摩尔质量302.41 g·mol−1
3D模型（JSmol）
熔点186至189 °C（367至372 °F） [1]
  • Oc1cc3c(cc1OC)[C@H]2CC[C@@]4([C@@H](O)CC[C@H]4[C@@H]2CC3)C
  • InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1 checkY
  • Key:CQOQDQWUFQDJMK-SSTWWWIQSA-N checkY

参考资料
  1. Minhang Xin, Qidong You, Hua Xiang. . Steroids. 2010-01, 75 (1): 53–56 [2021-01-26]. doi:10.1016/j.steroids.2009.09.013 （英语）.
  2. Pribluda VS, Gubish ER, Lavallee TM, Treston A, Swartz GM, Green SJ. . Cancer Metastasis Reviews. 2000, 19 (1–2): 173–9. PMID 11191057. S2CID 20055299. doi:10.1023/a:1026543018478.
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