7,8-二羟基黄酮

7,8-二羟基黄酮英語:,缩写7,8-DHF,也称为 Tropoflavin)是一种天然黄酮,存在于長柄菊(学名:Tridax procumbens)等植物中[2][3][4]

Tropoflavin
藥物動力學數據
生物利用度~5% (in mice)[1]
生物半衰期< 30 minutes (in mice)[1]
识别
  • 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one
CAS号38183-03-8  checkY
PubChem CID
ChemSpider
UNII
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.048.903
化学
化学式C15H10O4
摩尔质量254.24 g·mol−1
3D模型(JSmol
  • c1ccc(cc1)c2cc(=O)c3ccc(c(c3o2)O)O
  • InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
  • Key:COCYGNDCWFKTMF-UHFFFAOYSA-N

参考文献

  1. US application 20150274692,Keqiang Ye,「7,8-Dihydoxyflavone and 7,8-substituted flavone derivatives, compositions, and methods related thereto」,发表于2015-10-01,指定于Emory University
  2. Andero, R.; Ressler, K.J. . Genes, Brain and Behavior. 2012, 11 (5): 503–512. ISSN 1601-1848. PMC 3389160可免费查阅. PMID 22530815. doi:10.1111/j.1601-183X.2012.00801.x.
  3. Colombo, Paola S.; Flamini, Guido; Christodoulou, Michael S.; Rodondi, Graziella; Vitalini, Sara; Passarella, Daniele; Fico, Gelsomina. (PDF). Phytochemistry. 2014, 98: 151–159. ISSN 0031-9422. PMID 24345641. doi:10.1016/j.phytochem.2013.11.018. hdl:2434/233766可免费查阅.
  4. Cell Press. . ScienceDaily. 2015 [2015-03-19]. (原始内容存档于2021-07-26).
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