ABT-418

ABT-418是一种有机化合物,化学式为C9H14N2O,由美國雅培开发,可用作益智藥抗焦慮藥[1][2][3][4][5]

ABT-418
识别
  • 3-Methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,2-oxazole
CAS号147402-53-7  ☒N
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
化学
化学式C9H14N2O
摩尔质量166.22
3D模型(JSmol
  • CC1=NOC(=C1)[C@@H]2CCCN2C
  • InChI=1S/C9H14N2O/c1-7-6-9(12-10-7)8-4-3-5-11(8)2/h6,8H,3-5H2,1-2H3/t8-/m0/s1 checkY
  • Key:ILLGYRJAYAAAEW-QMMMGPOBSA-N checkY

参考文献

  1. Arneric SP, Sullivan JP, Briggs CA, Donnelly-Roberts D, Anderson DJ, Raszkiewicz JL, et al. . The Journal of Pharmacology and Experimental Therapeutics. July 1994, 270 (1): 310–318. PMID 7518514.
  2. Decker MW, Brioni JD, Sullivan JP, Buckley MJ, Radek RJ, Raszkiewicz JL, et al. . The Journal of Pharmacology and Experimental Therapeutics. July 1994, 270 (1): 319–328. PMID 7913497.
  3. Brioni JD, O'Neill AB, Kim DJ, Buckley MJ, Decker MW, Arneric SP. . The Journal of Pharmacology and Experimental Therapeutics. October 1994, 271 (1): 353–361. PMID 7965735.
  4. Prendergast MA, Terry AV, Jackson WJ, Marsh KC, Decker MW, Arneric SP, Buccafusco JJ. . Psychopharmacology. April 1997, 130 (3): 276–284. PMID 9151363. S2CID 34377165. doi:10.1007/s002130050240.
  5. Dallanoce C, Magrone P, Matera C, Lo Presti L, De Amici M, Riganti L, et al. . European Journal of Medicinal Chemistry. December 2010, 45 (12): 5594–5601. PMID 20932609. doi:10.1016/j.ejmech.2010.09.009.
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