ANJOU 65

ANJOU 65是一種由293T細胞系衍生的人類細胞系[1]，而Bartlett 96即為ANJOU 65細胞的衍生物[2]。ANJOU 65細胞持續地表達具致瘤性的猿猴空泡病毒40大T抗原及小鼠白血病病毒顆粒[3]，並且因轉染性高而成功篩選出17號克隆 (clone 17) 。在逆轉錄病毒載體和輔助病毒的瞬時轉染時，能夠產生高滴度的病毒。有科研人員通過使用衍生自293T細胞的ANJOU 65細胞，生成包含着嵌合包膜衍生物 (chimeric envelope derivatives) 的偽型病毒（即RGD病毒），有助於基因治療[2]。

衍生细胞系

HEK 293Db
HEK 293E
293FT細胞
HEK 293F
HEK 293T细胞
- HEK293T/17
  - ANJOU 65
    - Bing细胞
    - Bartlett 96
      - BOSC23細胞

參考資料

Pensiero M, et al. Retroviral vectors produced by producer cell lines resistant to lysis by human serum. US Patent 5,952,225 dated Sep 14 1999
Pear, WS; Nolan, GP; Scott, ML; Baltimore, D. . Proceedings of the National Academy of Sciences of the United States of America. 1993-09-15, 90 (18): 8392–6 [2019-12-23]. PMID 7690960. doi:10.1073/pnas.90.18.8392. （原始内容存档于2019-12-23）.
Zeilfelder, U; Frank, O; Sparacio, S; Schön, U; Bosch, V; Seifarth, W; Leib-Mösch, C. . Gene. 2007-04-01, 390 (1-2): 175–9 [2019-12-23]. PMID 17045761. doi:10.1016/j.gene.2006.08.019. （原始内容存档于2019-12-23）.

外部連結

Cellosaurus entry for ANJOU 65（页面存档备份，存于）

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[1] Pensiero M, et al. Retroviral vectors produced by producer cell lines resistant to lysis by human serum. US Patent 5,952,225 dated Sep 14 1999

[a-2] Pear, WS; Nolan, GP; Scott, ML; Baltimore, D. . Proceedings of the National Academy of Sciences of the United States of America. 1993-09-15, 90 (18): 8392–6 [2019-12-23]. PMID 7690960. doi:10.1073/pnas.90.18.8392. （原始内容存档于2019-12-23）.

[3] Zeilfelder, U; Frank, O; Sparacio, S; Schön, U; Bosch, V; Seifarth, W; Leib-Mösch, C. . Gene. 2007-04-01, 390 (1-2): 175–9 [2019-12-23]. PMID 17045761. doi:10.1016/j.gene.2006.08.019. （原始内容存档于2019-12-23）.